MYCOPHENOLIC ACID

Mycophenolic acid is the active metabolite of mycophenolate with identical immunosuppressive effects. Side effects include diarrhea, leukopenia, and teratogenicity. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of Action

MYCOPHENOLIC ACID exhibits a multivector biochemical action pattern, influencing enzymatic cascades, receptormediated signalling, intracellular ion behaviour, mitochondrial oxidative dynamics and transcriptional regulatory networks. Its structural characteristics suggest interaction with catalytic residues, allosteric pockets and regulatory scaffolds, enabling modulation of phosphorylation circuits, secondmessenger systems (cAMP, Ca²⁺, IP), ROS generation, membrane polarization and metabolicflux channeling.

Depending on biological context, MYCOPHENOLIC ACID may alter mitochondrial membrane potential, redox buffering capacity, calcium sequestration, cytoskeletal integrity, vesicle trafficking efficiency and transcriptionfactor activation, resulting in broad mechanistic adaptability across experimental systems.

Benefits and Advantages

This compound is highly valued in advanced biochemical and pharmacological research frameworks, including:

  • Highresolution receptorligand mapping and affinity prediction
  • Enzymekinetic profiling and catalyticpathway deconstruction
  • Mitochondrialstress testing, ATPflux analysis and ROSequilibrium studies
  • Integrated multiomics research: transcriptomics, metabolomics, proteomics, phosphoproteomics
  • Cytoskeletal modelling involving actin/tubulin regulation
  • Apoptosis, autophagy, necroptosis and ferroptosis signalling investigations
  • Structureactivity relationship (SAR) exploration and molecular optimisation
  • Pharmacodynamic simulations for mechanistic threshold and doseresponse studies

Side Effects and Risks

Possible laboratoryobserved risks include:

  • Redox imbalance with elevated ROS levels
  • Mitochondrial overactivation or respiratorychain suppression
  • Ionchannel dysregulation affecting Na⁺/K⁺/Ca²⁺ flow
  • Crossactivation or inhibition of unintended receptor systems
  • Cytoskeletal destabilisation and impaired membrane integrity
  • Dosedependent cytotoxicity or induction of apoptotic/autophagic pathways
  • Transcriptional instability and activation of inflammatory cascades (NF-κB, JNK, p38)

Strict biosafety handling, controlled dosing and regulated environmental conditions are required for all experimental use. Not intended for human or veterinary application.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C17H20O6

Molecular Weight

320.3 g/mol

CAS Number

24280-93-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Insoluble

Purity

Purity information is available upon request (COA).

Synonym

mycophenolic acid; 24280-93-1; Melbex; Mycophenolsaeure; Lilly-68618

IUPAC/Chemical Name

(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid

InChl Key

HPNSFSBZBAHARI-RUDMXATFSA-N

InChl Code

InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+

References

https://pubchem.ncbi.nlm.nih.gov/compound/446541;

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