MYCOPHENOLIC ACID

Mycophenolic acid is the active metabolite of mycophenolate with identical immunosuppressive effects. Side effects include diarrhea, leukopenia, and teratogenicity.

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Product Description


Mechanism of Action

MYCOPHENOLIC ACID (ID 26796) exhibits a multi‑vector biochemical action pattern, influencing enzymatic cascades, receptor‑mediated signalling, intracellular ion behaviour, mitochondrial oxidative dynamics and transcriptional regulatory networks. Its structural characteristics suggest interaction with catalytic residues, allosteric pockets and regulatory scaffolds, enabling modulation of phosphorylation circuits, second‑messenger systems (cAMP, Ca²⁺, IP₃), ROS generation, membrane polarization and metabolic‑flux channeling.

Depending on biological context, MYCOPHENOLIC ACID may alter mitochondrial membrane potential, redox buffering capacity, calcium sequestration, cytoskeletal integrity, vesicle trafficking efficiency and transcription‑factor activation, resulting in broad mechanistic adaptability across experimental systems.

Benefits and Advantages

This compound is highly valued in advanced biochemical and pharmacological research frameworks, including:

  • High‑resolution receptor–ligand mapping and affinity prediction
  • Enzyme‑kinetic profiling and catalytic‑pathway deconstruction
  • Mitochondrial‑stress testing, ATP‑flux analysis and ROS‑equilibrium studies
  • Integrated multi‑omics research: transcriptomics, metabolomics, proteomics, phosphoproteomics
  • Cytoskeletal modelling involving actin/tubulin regulation
  • Apoptosis, autophagy, necroptosis and ferroptosis signalling investigations
  • Structure–activity relationship (SAR) exploration and molecular optimisation
  • Pharmacodynamic simulations for mechanistic threshold and dose‑response studies

Side Effects and Risks

Possible laboratory‑observed risks include:

  • Redox imbalance with elevated ROS levels
  • Mitochondrial overactivation or respiratory‑chain suppression
  • Ion‑channel dysregulation affecting Na⁺/K⁺/Ca²⁺ flow
  • Cross‑activation or inhibition of unintended receptor systems
  • Cytoskeletal destabilisation and impaired membrane integrity
  • Dose‑dependent cytotoxicity or induction of apoptotic/autophagic pathways
  • Transcriptional instability and activation of inflammatory cascades (NF‑κB, JNK, p38)

Strict biosafety handling, controlled dosing and regulated environmental conditions are required for all experimental use. Not intended for human or veterinary application.

Datasheet


Molecular Formula

C17H20O6

Molecular Weight

320.3 g/mol

CAS Number

24280-93-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Insoluble

Purity

Purity information is available upon request (COA).

Synonym

mycophenolic acid; 24280-93-1; Melbex; Mycophenolsaeure; Lilly-68618

IUPAC/Chemical Name

(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid

InChl Key

HPNSFSBZBAHARI-RUDMXATFSA-N

InChl Code

InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+

References

https://pubchem.ncbi.nlm.nih.gov/compound/446541;

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