ESERIN BASE
Eserine (physostigmine) base is a reversible acetylcholinesterase inhibitor improving cholinergic function, used in glaucoma and anticholinergic toxicity. Side effects include sweating, bradycardia, and abdominal cramps. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Physostigmine is a reversible acetylcholinesterase (AChE) inhibitor. By preventing the breakdown of acetylcholine, it increases cholinergic neurotransmission at muscarinic and nicotinic receptors. It crosses the bloodbrain barrier and enhances central cholinergic tone.
Benefits and Advantages
Used in cholinesteraseinhibition studies, CNS cholinergicpathway modelling, antidotemechanism research, and neuromusculartransmission assays.
Side Effects and Risks
Risks include bradycardia, bronchospasm, excessive salivation, seizures (overdose) and cholinergic crisis. Handle with AChEinhibitor precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C23H29N3O2 |
|---|---|
| Molecular Weight | 235.33 g/mol |
| CAS Number | 57-47-6 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | (3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate; (3,4,8B-Trimethyl-2,3A-Dihydro-1H-Pyrrolo(2,3-B)Indol-7-Yl) N-Methylcarbamate; RefChem:1050057; 1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate; CHEMBL11773 |
| IUPAC/Chemical Name | 3-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyridin-4-yl)carbamate |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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