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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cyclovirobuxin D is a steroidal alkaloid from *Buxus* species with cardiotonic, antiinflammatory and antitumor properties. It modulates ion channels, enhances Ca²⁺ influx, affects mitochondrial potential and interferes with apoptosisregulating pathways.
Benefits and Advantages
Used in cardiotonic research, ionchannel modulation studies, mitochondrialfunction assays, and cancercell apoptosis modelling.
Side Effects and Risks
Risks include cardiotoxicity, arrhythmias, neurotoxicity and hepatotoxicity. Handle with potent steroidalalkaloid precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C26H40N2O5 |
|---|---|
| Molecular Weight | 402.7 g/mol |
| CAS Number | 860-79-7 |
| Storage Condition | PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for … expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties …) that bears appropriate label. An inventory … should be kept, showing quantity of carcinogen & date it was acquired … Facilities for dispensing … should be contiguous to storage area. /Chemical Carcinogens/ |
| Solubility | less than 1 mg/mL at 73 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cyclovirobuxine D; Cyclovirobuxine; 860-79-7; Bebuxine; Cyclovirobuxine-D |
| IUPAC/Chemical Name | (1S,3R,6S,8R,11S,12S,14R,15S,16R)-7,7,12,16-tetramethyl-6-(methylamino)-15-[(1S)-1-(methylamino)ethyl]pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-ol |
| InChl Key | GMNAPBAUIVITMI-ABNIRSKTSA-N |
| InChl Code | InChI=1S/C26H46N2O/c1-16(27-6)21-17(29)14-24(5)19-9-8-18-22(2,3)20(28-7)10-11-25(18)15-26(19,25)13-12-23(21,24)4/h16-21,27-29H,8-15H2,1-7H3/t16-,17+,18-,19-,20-,21-,23+,24-,25+,26-/m0/s1 |
| References |
3D Conformer.
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