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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cholic acid is a primary bile acid that facilitates lipid emulsification, micelle formation and absorption of dietary fats and fatsoluble vitamins. It regulates FXR and TGR5 receptors, modulates hepatic bileacid synthesis and influences glucoselipid homeostasis.
Benefits and Advantages
Used in bileacid signalling research, FXR/TGR5 pathway studies, livermetabolism models, in vitro digestivelipid research, micelleformation studies and cholestaticdisease modelling.
Side Effects and Risks
Risks include pruritus, diarrhea, abdominal discomfort and potential hepatotoxicity in impaired bileacid metabolism. Handle with biologically active lipidcompound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C24H40O5 |
|---|---|
| Molecular Weight | 408.6 g/mol |
| CAS Number | 81-25-4 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Storage class (TRGS 510): Non Combustible Solids. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cholic acid; 81-25-4; Cholalic acid; Colalin; Cholalin |
| IUPAC/Chemical Name | (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
| InChl Key | BHQCQFFYRZLCQQ-OELDTZBJSA-N |
| InChl Code | InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1 |
| References |
3D Conformer.
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