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Product Description
Mechanism of Action
Cholic acid is a primary bile acid that facilitates lipid emulsification, micelle formation and absorption of dietary fats and fat‑soluble vitamins. It regulates FXR and TGR5 receptors, modulates hepatic bile‑acid synthesis and influences glucose‑lipid homeostasis.
Benefits and Advantages
Used in bile‑acid signalling research, FXR/TGR5 pathway studies, liver‑metabolism models, in vitro digestive‑lipid research, micelle‑formation studies and cholestatic‑disease modelling.
Side Effects and Risks
Risks include pruritus, diarrhea, abdominal discomfort and potential hepatotoxicity in impaired bile‑acid metabolism. Handle with biologically active lipid‑compound precautions.
Datasheet
| Molecular Formula | C24H40O5 |
|---|---|
| Molecular Weight | 408.6 g/mol |
| CAS Number | 81-25-4 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Storage class (TRGS 510): Non Combustible Solids. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cholic acid; 81-25-4; Cholalic acid; Colalin; Cholalin |
| IUPAC/Chemical Name | (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
| InChl Key | BHQCQFFYRZLCQQ-OELDTZBJSA-N |
| InChl Code | InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1 |
| References |
3D Conformer.
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