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Product Description
Mechanism of action
Baracoumin appears to be a coumarinderived compound with structural similarity to dicoumarol and other vitaminKantagonist scaffolds. These compounds inhibit vitamin K⁺ epoxide reductase (VKOR), preventing the regeneration of reduced vitamin K⁺ needed for carboxylation of clotting factors II, VII, IX and X. The result is diminished production of functional coagulation proteins.
Benefits and advantages
Coumarin derivatives are essential in anticoagulation research, VKOR binding studies, haemostasis modelling and therapeuticwindow investigations. They also support structureactivity analyses for nextgeneration oral anticoagulants.
Side effects and risks
Risks may include excessive anticoagulation, bleeding tendencies, hepatic disturbances and drug interactions affecting clotting factor turnover. Handle using anticoagulantgrade containment.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C20H16O5 |
|---|---|
| Molecular Weight | 336.3 g/mol |
| CAS Number | 66-76-2 |
| Storage Condition | Dicumarol should be stored in well-closed containers at a temperature below 40 degrees C (104 °F), preferably 15 to 30 °C (59 to 86 °F), and kept away from direct sunlight. The manufacturer recommends storage below 25 °C (77 °F). |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | dicumarol; dicoumarol; 66-76-2; Bishydroxycoumarin; melitoxin |
| IUPAC/Chemical Name | 4-hydroxy-3-[(4-hydroxy-2-oxochromen-3-yl)methyl]chromen-2-one |
| InChl Key | DOBMPNYZJYQDGZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H12O6/c20-16-10-5-1-3-7-14(10)24-18(22)12(16)9-13-17(21)11-6-2-4-8-15(11)25-19(13)23/h1-8,20-21H,9H2 |
| References |
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