AESCIN
Aescin is a natural saponin extracted from horse chestnut with anti‑inflammatory and venotonic properties. It reduces capillary permeability and improves venous tone, used for chronic venous insufficiency and edema. Benefits include reduced swelling and improved circulation. Side effects may include gastrointestinal discomfort, dizziness, or allergic reactions.
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Product Description
Mechanism of action
AESCIN is a pharmacologically active compound used in specialised medical or biochemical applications. Its mechanism of action involves modulation of specific cellular pathways, receptor interactions or enzyme systems depending on its structural class. In professional environments it is applied to influence defined metabolic, neurological, endocrine or immunological processes.
Benefits and advantages
AESCIN is valued for its predictable biochemical behaviour, defined purity profile and suitability for advanced formulation or research use. It provides targeted activity relevant to its therapeutic or analytical category, offering consistent performance under controlled conditions. The compound is often incorporated into protocols requiring high specificity or reproducibility.
Side effects and risks
Potential risks depend on the pharmacological class of AESCIN. These may include organ‑specific toxicity, allergic reactions, metabolic disturbances or interactions with other active substances. Because potency and toxicity can vary, handling and use are strictly limited to trained professionals operating within regulated laboratory or manufacturing settings.
Datasheet
| Molecular Formula | C55H86O24 |
|---|---|
| Molecular Weight | 1131.3 g/mol |
| CAS Number | 11072-93-8 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. |
| Solubility | In water, 60.2 mg/L at 25 °C |
| Purity | Purity information is available upon request (COA). |
| Synonym | Aescin; 6-[[9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-(2-methylbut-2-enoyloxy)-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxane-2-carboxylic acid; 6-((9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-(2-methylbut-2-enoyloxy)-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl)oxy)-4-hydroxy-3,5-bis((3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy)oxane-2-carboxylic acid; RefChem:553130; Aescin [German] |
| IUPAC/Chemical Name | 6-[[9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-(2-methylbut-2-enoyloxy)-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxane-2-carboxylic acid |
| InChl Key | AXNVHPCVMSNXNP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70) |
| References |
3D Conformer.
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