MESTRANOL
Mestranol is a synthetic estrogen used in combined oral contraceptives, converted to ethinylestradiol in the body. Benefits include effective ovulation suppression. Side effects include nausea, breast tenderness, clotting risk, and mood changes. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
MESTRANOL displays a broad and multiaxis biochemical interaction profile characterised by modulation of enzymatic networks, receptormediated signalling, intracellular ion regulation, mitochondrial bioenergetics and transcriptional pathway governance. Its structural features suggest interactions with catalytic and regulatory proteins, leading to changes in phosphorylation cycles, metabolic flux, mitochondrial redox balance, calciumsignalling behaviour and stressresponse activation. Depending on cellular environment and concentration, the compound may act as an activator, inhibitor or regulatory modulator.
Benefits and Advantages
This compound supports a wide range of , including:
- Receptorligand affinity profiling and bindingsite mapping
- Enzymecascade modelling and catalyticdomain interaction studies
- Mitochondrialfunction assays, oxidativestress evaluation and metabolicflux tracking
- Transcriptomic, proteomic and metabolomic investigation for pathway mapping
- Apoptosis / autophagy pathway research and cellularstress modelling
- Highresolution mechanismofaction studies and SAR exploration
Side Effects and Risks
Potential risks include oxidative imbalance, mitochondrial overload, ionchannel dysregulation, receptor crosstalk, cytoskeletal disruption and dosedependent cytotoxicity. At elevated exposure levels, the compound may induce apoptosis, autophagy, inflammatory signalling, metabolic reprogramming or transcriptional instability. Proper laboratory controls and strict biosafety procedures are required for handling.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H26O2 |
|---|---|
| Molecular Weight | 310.4 g/mol |
| CAS Number | 72-33-3 |
| Storage Condition | Store in a dry place below 25 °C away from direct sunlight. |
| Solubility | In double-distilled water, 0.32 mg/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | mestranol; 72-33-3; Norquen; Ovastol; Menophase |
| IUPAC/Chemical Name | (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol |
| InChl Key | IMSSROKUHAOUJS-MJCUULBUSA-N |
| InChl Code | InChI=1S/C21H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3/t17-,18-,19+,20+,21+/m1/s1 |
| References |
3D Conformer.
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