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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Estriol (E3) is a weaker estrogen produced mainly during pregnancy. It binds ERα/ERβ with lower affinity than estradiol but still regulates reproductive and urogenital tissues through transcriptional modulation and membrane‑initiated signalling.
Benefits and Advantages
Used in low‑potency estrogen research, mucosal‑tissue modelling, ER‑ligand affinity studies, and selective‑estrogen pharmacology.
Side Effects and Risks
Risks include mild nausea, breast tenderness and low but present thrombotic risk. Handle with low‑potency estrogen precautions.
Datasheet
| Molecular Formula | C18H24O3 |
|---|---|
| Molecular Weight | 288.4 g/mol |
| CAS Number | 50-27-1 |
| Storage Condition | Do not store above 25 °C. |
| Solubility | Slightly soluble in ethyl ether, benzene, trifluoroacetic acid; very soluble in pyridine |
| Purity | Purity information is available upon request (COA). |
| Synonym | estriol; 50-27-1; Oestriol; Trihydroxyestrin; Aacifemine |
| IUPAC/Chemical Name | (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol |
| InChl Key | PROQIPRRNZUXQM-ZXXIGWHRSA-N |
| InChl Code | InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1 |
| References |
3D Conformer.
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