DHEA (7-KETO)
Dehydrostreptomycin is an aminoglycoside antibiotic inhibiting bacterial protein synthesis, used in veterinary medicine. Side effects include ototoxicity and nephrotoxicity.
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Product Description
Mechanism of Action
7‑Keto‑DHEA is an oxygenated metabolite of dehydroepiandrosterone that does **not convert** into sex steroids. It modulates thermogenic enzymes, including mitochondrial glycerol‑3‑phosphate dehydrogenase and malic enzyme, and influences thyroid‑hormone signalling pathways, enhancing metabolic rate without androgenic effects. It also interacts with immune pathways, increasing certain T‑cell functions and modulating cytokine patterns.
Benefits and Advantages
Used in metabolic‑rate modelling, thermogenesis studies, adipocyte‑regulation research, immune‑modulation assays, and endocrine‑precursor pathway investigations where non‑androgenic activity is required.
Side Effects and Risks
Risks include mild GI discomfort, headaches, insomnia, irritability and rare hepatic enzyme elevations. Handle with steroid‑metabolite precautions.
Datasheet
| Molecular Formula | C19H26O3 |
|---|---|
| Molecular Weight | 302.41 g/mol |
| CAS Number | 125941-87-9 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | RefChem:930510; R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol; 87075-17-0; SCH-23390; SCH 23390 |
| IUPAC/Chemical Name | 3-acetyl-7-oxo-DHEA |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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