About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP Manufacturers
Let us handle your sourcing / supply activities. For years we have sourced specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
We are committed to supplying high-quality GMP products with logistics accoring to GDP regulations
Product Description
Mechanism of Action
SECNIDAZOL (ID 27429) displays a multidimensional biochemical activity profile integrating modulation of enzymatic pathways, receptor‑mediated signalling, mitochondrial bioenergetics, oxidative‑stress homeostasis, ion‑channel dynamics, membrane structural behaviour and transcription‑factor regulation. Structural modelling suggests interactions with catalytic residues, allosteric microdomains, transmembrane helices, signalling cofactors and cytoskeletal complexes. These interactions enable influence over phosphorylation cascades, second‑messenger flux (Ca²⁺, IP₃, DAG, cAMP), ROS balance, ATP turnover, membrane‑potential stability and organelle stress‑response thresholds.
Benefits and Applications
- Receptor–ligand affinity analysis and docking studies
- Enzyme‑kinetic profiling and catalytic‑flux pathway mapping
- Mitochondrial‑function modelling and ATP/ROS system evaluation
- Transcriptomic, metabolomic, proteomic and phosphoproteomic profiling
- Cytoskeletal‑architecture and membrane‑dynamics exploration
- Apoptosis, autophagy, necroptosis and ferroptosis pathway modelling
- SAR/QSAR modelling and compound‑optimisation workflows
- Mechanistic pharmacodynamics and dose–response simulation
Side Effects and Risks
- Oxidative‑stress imbalance and elevated ROS
- Mitochondrial overload or respiratory‑chain suppression
- Disruption of Ca²⁺/Na⁺/K⁺ ion‑homeostasis
- Unintended receptor cross‑talk or inhibitory signal interference
- Cytoskeletal destabilisation and membrane‑integrity reduction
- Dose‑dependent cytotoxicity or programmed‑cell‑death activation
- Transcriptional and epigenetic instability
- Inflammatory‑cascade activation (NF‑κB, MAPK, JNK)
Datasheet
| Molecular Formula | C7H11N3O3 |
|---|---|
| Molecular Weight | 185.18 g/mol |
| CAS Number | 3366-95-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | >27.8 [ug/mL] (The mean of the results at pH 7.4) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Secnidazole; 3366-95-8; Secnidazol; Flagentyl; 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol |
| IUPAC/Chemical Name | 1-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol |
| InChl Key | KPQZUUQMTUIKBP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C7H11N3O3/c1-5(11)4-9-6(2)8-3-7(9)10(12)13/h3,5,11H,4H2,1-2H3 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
