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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
METRONIDAZOLE BENZOATE demonstrates an extensive, multiaxis biochemical activity profile involving coordinated modulation of receptormediated signalling, enzymeregulated catalytic cascades, mitochondrial bioenergetics, intracellular ion regulation, and transcriptomic pathway dynamics. Its physicochemical properties support highaffinity interactions with both catalytic and regulatory protein domains, enabling interference with phosphorylationdephosphorylation cycles, secondmessenger turnover (cAMP, IP, DAG, Ca²⁺), and redoxequilibrium systems.
In cellular environments, METRONIDAZOLE BENZOATE may influence mitochondrial membrane potential, ATP synthesis efficiency, ROS generation and antioxidant neutralisation capacity. In addition, structuralprotein interactions can modify cytoskeletal arrangement, impacting cell motility, vesicular trafficking, and mechanical signalling. The compound may further modulate chromatin accessibility, transcription factor binding profiles, epigenetic markers, and geneexpression stability.
Benefits and Advantages
Because of its reproducible biochemical footprint, METRONIDAZOLE BENZOATE is an important tool across advanced research domains, including:
- Detailed receptorligand binding analysis and structural docking validation
- Highdefinition enzyme kinetics and catalyticdomain pathway mapping
- Mitochondrial respiration modelling, ATPflux analysis and oxidativestress pathway evaluation
- Transcriptomic, proteomic and metabolomic integration studies for fullpathway profiling
- Apoptosis, necroptosis and autophagyrelated signalling research
- Cytoskeletaldynamics studies involving actin, tubulin and intermediate filaments
- Highresolution SAR (structureactivity relationship) investigations for molecular optimisation
- Pharmacodynamic modelling for doseresponse, thresholdactivation and mechanistic benchmarking
Side Effects and Risks
Potential risks include:
- Redox imbalance and excessive ROS accumulation
- Mitochondrial overload or respiratorychain suppression
- Transcriptional pathway disruption or epigenetic instability
- Interference with ionchannel behaviour and calciumhandling regulation
- Cytoskeletal destabilisation and impaired membrane integrity
- Dosedependent cytotoxicity, apoptosis or autophagy induction
- Activation of inflammatory signalling cascades such as NF-κB, JNK, or p38
Extended exposure or elevated dosing may trigger metabolic rewiring, organelle stress responses, or longterm alterations in cellular signalling architecture. Strict biosafety protocols, controlled handling, and regulated exposure windows are required.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C13H11N3O4 |
|---|---|
| Molecular Weight | 275.26 g/mol |
| CAS Number | 13182-89-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Metronidazole benzoate; 13182-89-3; Benzoyl metronidazole; 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate; Klion suspension |
| IUPAC/Chemical Name | 2-(2-methyl-5-nitroimidazol-1-yl)ethyl benzoate |
| InChl Key | CUUCCLJJOWSASK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C13H13N3O4/c1-10-14-9-12(16(18)19)15(10)7-8-20-13(17)11-5-3-2-4-6-11/h2-6,9H,7-8H2,1H3 |
| References |
3D Conformer.
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