About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
MECLOCYCLINE SULFOSALICYLATE exhibits a multilayered biochemical interaction profile involving modulation of enzyme cascades, receptorregulated signalling, mitochondrial bioenergetics, redoxstate equilibrium, membranepotential dynamics and transcriptionfactor activation. Depending on concentration and cellular context, the compound can influence phosphorylation cycles, alter calcium signalling thresholds, disrupt or stabilise cytoskeletal structures, and reprogram metabolic flux pathways.
Benefits and Advantages
This compound is widely used in advanced mechanistic research, including:
- Receptorligand interaction analysis and allostericbinding studies
- Enzymekinetic mapping and catalyticdomain investigation
- Mitochondrialfunction, ROSbalance and redoxmodulation assays
- Transcriptomic, proteomic and metabolomic profiling
- Cellularstress signalling, apoptosis/autophagy modelling and membranedynamics studies
- Pharmacodynamic simulation, SAR evaluation and earlystage compound screening
Side Effects and Risks
Possible risks include mitochondrial overload, oxidativestress imbalance, ionchannel disruption, metabolic pathway misregulation, receptor crosstalk, and dosedependent cytotoxicity. At higher exposure, apoptosis, autophagy, transcriptional destabilisation or inflammationpathway activation may occur. Use only with strict laboratory safety procedures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C29H27ClN2O14S |
|---|---|
| Molecular Weight | 695.0 g/mol |
| CAS Number | 73816-42-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Meclocycline sulfosalicylate; Meclocycline sulfosalicylate salt; 73816-42-9; Meclan; Meclutin |
| IUPAC/Chemical Name | (4S,4aR,5S,5aR,12aR)-7-chloro-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;2-hydroxy-5-sulfobenzoic acid |
| InChl Key | WVJKUGVVYXCLFV-CCHMMTNSSA-N |
| InChl Code | InChI=1S/C22H21ClN2O8.C7H6O6S/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30;8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h4-5,10,14-15,17,26-28,31,33H,1H2,2-3H3,(H2,24,32);1-3,8H,(H,9,10)(H,11,12,13)/t10-,14-,15+,17+,22+;/m1./s1 |
| References |
3D Conformer.
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