LECOFLOXACIN HCL

Lecofloxacin HCl is a fluoroquinolone antibiotic inhibiting bacterial DNA replication. Benefits include broad-spectrum action. Side effects include GI upset, dizziness, and tendon-related effects. Only GMP materials will be supplied, logistics all according to GDP.

SKU: d1a72104ecb1 Category: Tag:

Product Description


Mechanism of Action

LECOFLOXACIN HCL exhibits a structured and multilayered biochemical activity profile involving modulation of enzymatic cascades, receptorbinding dynamics, intracellular signalling architecture, and metabolicflux regulation. Its molecular characteristics indicate potential interactions with catalytic pockets, allosteric surfaces, and regulatory protein domains. Through these interactions, the compound influences phosphorylation patterns, mitochondrial bioenergetics, oxidativestress networks, membrane potential stabilization, and transcriptional pathway responsiveness.

In cellular systems, mechanistic effects may include modulation of calcium flux, ROS equilibrium, structuralprotein turnover, and adaptive stressresponse activation. The compound may act as a pathway booster, suppressor, or modulator depending on dosing, cellular environment, and metabolic state.

Benefits and Advantages

This compound is widely used in biochemical, pharmacological and mechanistic research settings, including:

  • Receptorligand interaction studies and affinitymapping assays
  • Enzyme kinetics and catalyticpathway modelling
  • Mitochondrialfunction, ROSregulation and redoxbalance experiments
  • Transcriptomic, proteomic and metabolomic profiling
  • Cellstress signalling, apoptosis/autophagy pathway mapping and cytoskeletaldynamics studies
  • Pharmacodynamic simulation and SAR (structureactivity relationship) analysis

Side Effects and Risks

Risks may include unintended oxidative imbalance, mitochondrial overload, receptor crosstalk effects, disruption of ionchannel homeostasis, and dosedependent cytotoxicity. At elevated concentrations, the compound may trigger apoptosis, autophagy, or compensatory metabolic rewiring. Longterm exposure can influence transcriptional stability, signalling thresholds, and cellular resilience.

Use only in controlled laboratory environments following strict biosafety and handling protocols. Not intended for human or veterinary use.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C18H21ClFN3O4

Molecular Weight

401.82 g/mol

CAS Number

122111-03-9

Storage Condition

Store at 2-8°C

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

Dothiepin; 113-53-1; DTXSID2022961; CHEBI:36798; RefChem:920635

IUPAC/Chemical Name

(ˆ’)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hydrochloride

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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