ISOCONAZOLE BASE

Isoconazole base is an antifungal inhibiting ergosterol biosynthesis. Side effects include burning, redness, and irritation.

SKU: d29ca1162ba2 Category: Tag:

Product Description


Mechanism of Action

ISOCONAZOLE BASE (ID 26466) exhibits complex multi‑pathway biochemical interactions involving receptor‑level modulation, regulatory enzyme interference, intracellular signalling adjustment and transcriptomic pathway influence. Its physicochemical profile suggests affinity for catalytic and regulatory protein domains, enabling disruption or enhancement of phosphorylation cycles, redox‑state balance, and mitochondrial performance. In several experimental systems, the compound demonstrates capacity to alter calcium signalling, membrane potential, structural‑protein dynamics and cellular metabolic flux.

Benefits and Advantages

This compound supports high‑resolution biochemical modelling and is suitable for use in:

  • Receptor‑ligand binding studies and pathway validation
  • Metabolic‑flux assays, mitochondrial‑stress evaluations and ROS‑regulation research
  • Multi‑omics profiling (transcriptomics, metabolomics, proteomics)
  • Stress‑response signalling, kinase/phosphatase cascade mapping and cytoskeletal dynamics analysis
  • Early‑phase pharmacodynamic screening and SAR exploration

Side Effects and Risks

Potential risks include redox imbalance, mitochondrial overload, cytoskeletal disruption, altered membrane integrity, aberrant calcium flux, and dose‑dependent cytotoxicity. At elevated concentrations, the compound may induce apoptosis, autophagy, or transcriptional stress responses. Use only under strict laboratory conditions with appropriate biosafety protocols and controlled exposure.

Datasheet


Molecular Formula

C18H15Cl3N2O

Molecular Weight

414.1 g/mol

CAS Number

27523-40-6

Storage Condition

Store at 2-8°C

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

Isoconazole; 27523-40-6; Isoconazol; Isoconazolum; Travogen

IUPAC/Chemical Name

(1-[(dichloro-phenyl)methyl]-1H-imidazolyl)methyl phenyl ether

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

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