GLIPIZIDE
Glipizide is a sulfonylurea that lowers blood glucose by stimulating beta‑cell insulin release. Side effects include hypoglycemia, headache, and GI discomfort.
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Product Description
Mechanism of Action
Glipizide is a sulfonylurea that binds SUR1 on pancreatic KATP channels, enhancing insulin secretion from beta cells and improving glucose control.
Benefits and Advantages
Used in pancreatic-islet research, insulin-secretion modelling, metabolic studies and endocrine pharmacology.
Side Effects and Risks
Hypoglycemia, weight gain and rare cholestatic reactions.
Datasheet
| Molecular Formula | C21H27N5O4S |
|---|---|
| Molecular Weight | 445.5 g/mol |
| CAS Number | 29094-61-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | glipizide; 29094-61-9; Glucotrol; Glydiazinamide; Glibenese |
| IUPAC/Chemical Name | N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide |
| InChl Key | ZJJXGWJIGJFDTL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28) |
| References |
3D Conformer.
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