About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Erythromycin is a macrolide antibiotic that binds the 50S ribosomal subunit at the peptideexit tunnel, blocking translocation and inhibiting protein synthesis. It is active against many grampositive organisms and atypical pathogens.
Benefits and Advantages
Used in ribosomalbinding assays, macrolideSAR analysis, bacterialproteinsynthesis modelling, and antimicrobialresistance research.
Side Effects and Risks
Risks include GI upset, QT prolongation, cholestatic hepatitis and drugdrug interactions via CYP3A4 inhibition. Handle with macrolideantibiotic precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C37H67NO13 |
|---|---|
| Molecular Weight | 733.9 g/mol |
| CAS Number | 114-07-8 |
| Storage Condition | Commercially available erythromycin topical solutions and gels should be stored at 15 – 30 °C; exposure to heat or open flames should be avoided. The topical ointment should be stored at a temperature less than 27 °C. |
| Solubility | Soluble in water at 2mg/ml |
| Purity | Purity information is available upon request (COA). |
| Synonym | erythromycin; 114-07-8; Erythromycin A; E-Mycin; Abomacetin |
| IUPAC/Chemical Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione |
| InChl Key | ULGZDMOVFRHVEP-RWJQBGPGSA-N |
| InChl Code | InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 |
| References |
3D Conformer.
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