ERYTHROMYCIN ETHYL SUCCINATE

Erythromycin lauryl sulfate is an antimicrobial salt form used topically. Side effects include skin dryness, irritation, and peeling. Only GMP materials will be supplied, logistics all according to GDP.

SKU: a2d7d5d7ef0d Category: Tag:

Product Description


Mechanism of Action

This acidresistant ester of erythromycin improves stability in gastric acid and ensures effective delivery of active drug to systemic circulation. Mechanism remains inhibition of the 50S ribosomal subunit.

Benefits and Advantages

Used in PK/PD macrolide modelling, esterstability studies, pediatric antimicrobial testing, and bacterialprotein synthesis inhibition research.

Side Effects and Risks

Risks include GI upset, mild hepatotoxicity and druginteraction potential. Handle with erythromycinester precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C43H75NO16

Molecular Weight

862.1 g/mol

CAS Number

1264-62-6

Storage Condition

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Solubility

FREELY SOL IN ACETONE & CHLOROFORM; SOL IN 95% ETHANOL & BENZENE; SPARINGLY SOL IN ETHER; VERY SLIGHTLY SOL IN WATER

Purity

Purity information is available upon request (COA).

Synonym

erythromycin ethylsuccinate; 1264-62-6; Erythromycin ethyl succinate; Erythrocin ethyl succinate; anamycin

IUPAC/Chemical Name

4-O-[(2S,3R,4S,6R)-4-(dimethylamino)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl] 1-O-ethyl butanedioate

InChl Key

NSYZCCDSJNWWJL-YXOIYICCSA-N

InChl Code

InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,32+,34+,35-,36-,37+,38-,40+,41-,42-,43-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/443953;

3D Conformer.

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