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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Erythromycin is a macrolide antibiotic that binds the 50S ribosomal subunit at the peptide‑exit tunnel, blocking translocation and inhibiting protein synthesis. It is active against many gram‑positive organisms and atypical pathogens.
Benefits and Advantages
Used in ribosomal‑binding assays, macrolide‑SAR analysis, bacterial‑protein‑synthesis modelling, and antimicrobial‑resistance research.
Side Effects and Risks
Risks include GI upset, QT prolongation, cholestatic hepatitis and drug–drug interactions via CYP3A4 inhibition. Handle with macrolide‑antibiotic precautions.
Datasheet
| Molecular Formula | C37H67NO13 |
|---|---|
| Molecular Weight | 733.9 g/mol |
| CAS Number | 114-07-8 |
| Storage Condition | Commercially available erythromycin topical solutions and gels should be stored at 15 – 30 °C; exposure to heat or open flames should be avoided. The topical ointment should be stored at a temperature less than 27 °C. |
| Solubility | Soluble in water at 2mg/ml |
| Purity | Purity information is available upon request (COA). |
| Synonym | erythromycin; 114-07-8; Erythromycin A; E-Mycin; Abomacetin |
| IUPAC/Chemical Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione |
| InChl Key | ULGZDMOVFRHVEP-RWJQBGPGSA-N |
| InChl Code | InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 |
| References |
3D Conformer.
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