ENOXACINE

Enoxacine is a fluoroquinolone effective against gram-negative bacteria. Side effects include dizziness, nausea, and photosensitivity. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of Action

Enoxacine is a fluoroquinolone that inhibits bacterial DNA gyrase (GyrA/GyrB) and topoisomerase IV, preventing DNA replication and segregation. It exhibits strong gramnegative activity and good intracellular penetration.

Benefits and Advantages

Used in DNAreplication inhibition studies, topoisomeraseinteraction assays, bacterialkinetics research, and resistancemutation profiling.

Side Effects and Risks

Risks include tendon rupture, neuropathy, CNS overstimulation, hepatotoxicity and QT prolongation. Handle with quinoloneclass precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H17FN2O3

Molecular Weight

320.32 g/mol

CAS Number

74011-58-8

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

enoxacin; 74011-58-8; Penetrex; Enoxacine; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid

IUPAC/Chemical Name

1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid

InChl Key

IDYZIJYBMGIQMJ-UHFFFAOYSA-N

InChl Code

InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3229;

3D Conformer.

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