DOXYCYCLINE HCL
Doxycycline HCl is a tetracycline antibiotic inhibiting bacterial protein synthesis. Side effects include photosensitivity, GI upset, and esophageal irritation. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Doxycycline hydrochloride is a tetracyclineclass antibiotic that binds the 30S ribosomal subunit, preventing aminoacyltRNA attachment and inhibiting bacterial protein synthesis. Its lipophilicity confers broad tissue distribution and activity against intracellular bacteria.
Benefits and Advantages
Used in proteintranslation inhibition studies, intracellular pathogen modelling, MMPinhibition assays, and broadspectrum antimicrobial mechanism investigations.
Side Effects and Risks
Risks include photosensitivity, GI irritation, esophageal erosion, hepatotoxicity and interaction with calciumcontaining products. Handle with tetracyclinecompound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C22H24N2O8·HCl |
|---|---|
| Molecular Weight | 480.9 g/mol |
| CAS Number | 10592-13-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Doxycycline hydrochloride; 10592-13-9; Doxycycline HCl; Doxigalumicina; Biocamycin |
| IUPAC/Chemical Name | (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride |
| InChl Key | PTNZGHXUZDHMIQ-CVHRZJFOSA-N |
| InChl Code | InChI=1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31);1H/t7-,10+,14+,15-,17-,22-;/m0./s1 |
| References |
3D Conformer.
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