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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Dihydrostreptomycin sulfate is an aminoglycoside antibiotic that binds to the 30S ribosomal subunit, inhibiting protein synthesis and causing mistranslation‑mediated bactericidal effects. Reduction of streptomycin improves stability but increases ototoxicity risk.
Benefits and Advantages
Used in aminoglycoside‑mechanism modelling, bacterial translation research, resistance‑pathway studies, and ribosomal‑binding assays.
Side Effects and Risks
Risks include irreversible hearing loss, vestibular dysfunction, nephrotoxicity and neuromuscular blockade. Handle with aminoglycoside‑class containment.
Datasheet
| Molecular Formula | C21H43N7O16S |
|---|---|
| Molecular Weight | 681.7 g/mol |
| CAS Number | 1425-61-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Streptomycin, dihydro-, sulfate; RefChem:1099086; Dihydrostreptomycin sulphate; 1425-61-2; Citrocil |
| IUPAC/Chemical Name | 2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;sulfuric acid |
| InChl Key | GSPKOIJAMLDYCY-RMIBZTJPSA-N |
| InChl Code | InChI=1S/C21H41N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1 |
| References |
3D Conformer.
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