CYCLACILLIN

Cyclacillin is an aminopenicillin antibiotic that inhibits bacterial cell wall synthesis and is used for respiratory and urinary infections. Side effects include rash, GI upset, and hypersensitivity reactions. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 8f85b62e8090 Category: Tag:

Product Description


Mechanism of Action

Cyclacillin is an aminopenicillin antibiotic that inhibits cellwall synthesis through binding to penicillinbinding proteins (PBPs). Its cyclohexyl side chain improves resistance to lactamase degradation and enhances oral stability compared with ampicillin.

Benefits and Advantages

Used in lactam SAR studies, grampositive susceptibility assays, oralbioavailability modelling, and PBPbinding mechanism investigations.

Side Effects and Risks

Risks include hypersensitivity reactions, GI upset, hepaticenzyme elevation and alteration of gut flora. Handle with lactam antibiotic precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C16H23N3O5S

Molecular Weight

341.4 g/mol

CAS Number

3485-14-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

1.90e+00 g/L

Purity

Purity information is available upon request (COA).

Synonym

CYCLACILLIN; ciclacillin; Vastcillin; 3485-14-1; Aminocyclohexylpenicillin

IUPAC/Chemical Name

(2S,5R,6R)-6-[(1-aminocyclohexanecarbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

InChl Key

HGBLNBBNRORJKI-WCABBAIRSA-N

InChl Code

InChI=1S/C15H23N3O4S/c1-14(2)9(12(20)21)18-10(19)8(11(18)23-14)17-13(22)15(16)6-4-3-5-7-15/h8-9,11H,3-7,16H2,1-2H3,(H,17,22)(H,20,21)/t8-,9+,11-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/19003;

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