CLINDAMYCIN HYDROCHLORID
Clindamycin hydrochloride inhibits bacterial protein synthesis, treating anaerobic and gram‑positive infections. Side effects include diarrhea, C. difficile risk, and rash.
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Product Description
Mechanism of Action
Clindamycin hydrochloride is a lincosamide antibiotic that binds the 50S ribosomal subunit and inhibits peptide‑chain elongation. It has excellent penetration into bone and anaerobic tissues. Effective against gram‑positive cocci and anaerobes.
Benefits and Advantages
Used in anaerobic‑bacteriology studies, ribosome‑target modelling, osteomyelitis research, toxin‑suppression studies (e.g., Streptococcal and Staphylococcal toxins) and intracellular pathogen assays.
Side Effects and Risks
Risks include C. difficile overgrowth, diarrhea, rash, hepatotoxicity and neutropenia. Handle as a potent protein‑synthesis inhibitor.
Datasheet
| Molecular Formula | C18H34ClN3O5S |
|---|---|
| Molecular Weight | 424.0 g/mol |
| CAS Number | 21462-39-5 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | SureCN722402; RefChem:1099296; (2S,4R)-N-(2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl)-1-methyl-4-propyl-pyrrolidine-2-carboxamide;hydrochloride; Dalacin (TN); AC1LCVGH |
| IUPAC/Chemical Name | Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propylpyrrolidin-2-yl)thio-L-threo-α-D-galacto-octopyranoside hydrochloride |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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