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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Ciclacillin is an aminopenicillin derivative that inhibits bacterial cell‑wall synthesis by binding PBPs and preventing peptidoglycan crosslinking. It demonstrates improved oral stability relative to ampicillin through structural cyclisation that protects the β‑lactam from hydrolysis.
Benefits and Advantages
Used in β‑lactam stability research, gram‑positive susceptibility studies, oral‑absorption modelling, PBP‑binding assays and aminopenicillin SAR comparisons.
Side Effects and Risks
Risks include allergic reactions, GI upset, hepatic enzyme elevation and alteration of gut flora. Handle following β‑lactam antimicrobial precautions.
Datasheet
| Molecular Formula | C16H23N3O5S |
|---|---|
| Molecular Weight | 341.4 g/mol |
| CAS Number | 3485-14-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 1.90e+00 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | CYCLACILLIN; ciclacillin; Vastcillin; 3485-14-1; Aminocyclohexylpenicillin |
| IUPAC/Chemical Name | (2S,5R,6R)-6-[(1-aminocyclohexanecarbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| InChl Key | HGBLNBBNRORJKI-WCABBAIRSA-N |
| InChl Code | InChI=1S/C15H23N3O4S/c1-14(2)9(12(20)21)18-10(19)8(11(18)23-14)17-13(22)15(16)6-4-3-5-7-15/h8-9,11H,3-7,16H2,1-2H3,(H,17,22)(H,20,21)/t8-,9+,11-/m1/s1 |
| References |
3D Conformer.
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