About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Cefodizime is a thirdgeneration cephalosporin with unique immunomodulatory properties in addition to classical lactam antibacterial action. It binds PBPs and inhibits bacterial cellwall crosslinking while demonstrating enhanced resistance to many lactamases. Its side chain contributes to improved stability and extended halflife. Some studies indicate immune-enhancing effects, including improved phagocytic activity and macrophage stimulation.
Benefits and advantages
Used in immunomodulation research, gramnegative susceptibility studies, lactam stability evaluations, PBP affinity profiling, respiratory-infection modelling, and macrophage-function studies. A reference molecule for immune-active cephalosporins.
Side effects and risks
Risks include hypersensitivity, diarrhoea, abnormal liver function tests, eosinophilia and rare haematologic abnormalities. Standard antimicrobial PPE applies.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C20H19N7O7S3 |
|---|---|
| Molecular Weight | 584.7 g/mol |
| CAS Number | 69739-16-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cefodizime; 69739-16-8; Cefodizima; Cefodizimum; CDZM |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | XDZKBRJLTGRPSS-BGZQYGJUSA-N |
| InChl Code | InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12-/t13-,17-/m1/s1 |
| References |
3D Conformer.
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