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Product Description
Mechanism of action
Cefodizime is a third‑generation cephalosporin with unique immunomodulatory properties in addition to classical β‑lactam antibacterial action. It binds PBPs and inhibits bacterial cell‑wall crosslinking while demonstrating enhanced resistance to many β‑lactamases. Its side chain contributes to improved stability and extended half‑life. Some studies indicate immune-enhancing effects, including improved phagocytic activity and macrophage stimulation.
Benefits and advantages
Used in immunomodulation research, gram‑negative susceptibility studies, β‑lactam stability evaluations, PBP affinity profiling, respiratory-infection modelling, and macrophage-function studies. A reference molecule for immune-active cephalosporins.
Side effects and risks
Risks include hypersensitivity, diarrhoea, abnormal liver function tests, eosinophilia and rare haematologic abnormalities. Standard antimicrobial PPE applies.
Datasheet
| Molecular Formula | C20H19N7O7S3 |
|---|---|
| Molecular Weight | 584.7 g/mol |
| CAS Number | 69739-16-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cefodizime; 69739-16-8; Cefodizima; Cefodizimum; CDZM |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | XDZKBRJLTGRPSS-BGZQYGJUSA-N |
| InChl Code | InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12-/t13-,17-/m1/s1 |
| References |
3D Conformer.
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