CEFMENOXIME HCL

Cefmenoxime hydrochloride is a cephalosporin inhibiting cell wall synthesis with broad gram‑negative activity. Side effects include rash, fever, and GI discomfort.

SKU: b41d525b44ea Category: Tag:

Product Description


Mechanism of action

Cefmenoxime hydrochloride is a third-generation cephalosporin with high stability to β-lactamases and strong activity against both gram-negative and gram-positive organisms. It targets PBPs and disrupts peptidoglycan crosslinking, leading to bactericidal cell-wall damage.

Benefits and advantages

Used in hospital-pathogen research, β-lactamase-stability studies, gram-negative susceptibility testing, cephalosporin SAR analysis, and PK/PD investigations of advanced-generation cephalosporins.

Side effects and risks

Risks include hypersensitivity, GI disturbances, hepatic enzyme alteration and selection of resistant subpopulations. Handle with antimicrobial compound safety measures.

Datasheet


Molecular Formula

C16H17N5O7S2Cl

Molecular Weight

1059.6 g/mol

CAS Number

75738-58-8

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Cefmenoxime hydrochloride; 75738-58-8; Cefmenoxime HCl; Cefmax; Cefmenoxime hemihydrochloride

IUPAC/Chemical Name

bis((6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid);hydrochloride

InChl Key

MPTNDTIREFCQLK-UNVJPQNDSA-N

InChl Code

InChI=1S/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h2*5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b2*21-8-;/t2*9-,13-;/m11./s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/11954009;

3D Conformer.

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