CEFMENOXIME HCL
Cefmenoxime hydrochloride is a cephalosporin inhibiting cell wall synthesis with broad gram‑negative activity. Side effects include rash, fever, and GI discomfort.
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Product Description
Mechanism of action
Cefmenoxime hydrochloride is a third-generation cephalosporin with high stability to β-lactamases and strong activity against both gram-negative and gram-positive organisms. It targets PBPs and disrupts peptidoglycan crosslinking, leading to bactericidal cell-wall damage.
Benefits and advantages
Used in hospital-pathogen research, β-lactamase-stability studies, gram-negative susceptibility testing, cephalosporin SAR analysis, and PK/PD investigations of advanced-generation cephalosporins.
Side effects and risks
Risks include hypersensitivity, GI disturbances, hepatic enzyme alteration and selection of resistant subpopulations. Handle with antimicrobial compound safety measures.
Datasheet
| Molecular Formula | C16H17N5O7S2Cl |
|---|---|
| Molecular Weight | 1059.6 g/mol |
| CAS Number | 75738-58-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cefmenoxime hydrochloride; 75738-58-8; Cefmenoxime HCl; Cefmax; Cefmenoxime hemihydrochloride |
| IUPAC/Chemical Name | bis((6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid);hydrochloride |
| InChl Key | MPTNDTIREFCQLK-UNVJPQNDSA-N |
| InChl Code | InChI=1S/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h2*5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b2*21-8-;/t2*9-,13-;/m11./s1 |
| References |
3D Conformer.
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