About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cefalotin is a parenteral first-generation cephalosporin that binds PBPs and inhibits transpeptidation in bacterial cell walls. It is effective against gram-positive cocci and some gram-negative bacilli. It is less stable to -lactamases compared to later-generation cephalosporins.
Benefits and Advantages
Used in antimicrobial-resistance modelling, PBP-selectivity studies, bactericidal-kinetics analysis, cephalosporin stability comparisons and veterinary/pathogen research.
Side Effects and Risks
Risks include hypersensitivity, nephrotoxicity (especially with rapid IV infusion), GI upset and injection-site reactions. Handle with -lactam antimicrobial safety protocols.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C16H16N2O6S2 |
|---|---|
| Molecular Weight | 396.4 g/mol |
| CAS Number | 153-61-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cephalothin; Cefalotin; 153-61-7; Cephalotin; Cefalothin |
| IUPAC/Chemical Name | (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | XIURVHNZVLADCM-IUODEOHRSA-N |
| InChl Code | InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1 |
| References |
3D Conformer.
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