CEFALOGLICIN
Cefaloglycin is a cephalosporin inhibiting cell wall synthesis. Benefits include broad activity. Side effects include GI upset and hypersensitivity.
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Product Description
Mechanism of Action
Cefaloglicin is an early-generation cephalosporin antibiotic that inhibits PBPs, disrupting bacterial cell-wall peptidoglycan synthesis and promoting osmotic lysis. It shows stronger activity against gram-positive organisms with limited gram-negative coverage.
Benefits and Advantages
Used in β-lactam mechanism comparisons, gram-positive PBPs studies, cephalosporin historical SAR research, MIC profiling and early cephalosporin pharmacology modelling.
Side Effects and Risks
Risks include hypersensitivity, GI irritation and occasional haematological changes. Handle under β-lactam antibiotic precautions.
Datasheet
| Molecular Formula | C16H17N5O5S2 |
|---|---|
| Molecular Weight | 439.47 g/mol |
| CAS Number | 5747-74-2 |
| Storage Condition | Store in a cool, dry place; protected from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | (6R,7R)-7-{[(2-amino-1,3,4-thiadiazol-5-yl)amino]acetamido}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | QXNDHRHTKVBKFP-ZXTJJVSNSA-N |
| References | PubChem; ChemBL; FDA substance registry; |
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