CEFALEXIN

Cefalexin is a cephalosporin antibiotic for respiratory, urinary, and skin infections. Side effects include diarrhea, rash, and rare anaphylaxis.

SKU: 26d0784d33f5 Category: Tag:

Product Description


Mechanism of Action

Cefalexin is a widely used first-generation cephalosporin that inhibits bacterial cell-wall synthesis by binding PBPs and blocking peptidoglycan crosslinking. It is highly effective against gram-positive cocci and some gram-negative species.

Benefits and Advantages

Used in bacteriology research, β-lactam-resistance pathway studies, cell-wall biosynthesis modelling, MIC profiling, biofilm inhibition testing and cephalosporin SAR research.

Side Effects and Risks

Risks include allergic reactions, GI upset, Clostridioides overgrowth, elevated liver enzymes and rare interstitial nephritis. Handle with routine antimicrobial precautions.

Datasheet


Molecular Formula

C16H17N3O4S

Molecular Weight

347.4 g/mol

CAS Number

15686-71-2

Storage Condition

Cephalexin capsules, tablets, and powder for oral suspension should be stored in tight containers at a temperature less than 40 °C, preferably between 15-30 °C. After reconstitution, cephalexin oral suspensions should be stored at 2-8 °C and discarded if not used within 2 wk.

Solubility

10mg/mL

Purity

Purity information is available upon request (COA).

Synonym

cephalexin; Cefalexin; 15686-71-2; Keflex; Cephacillin

IUPAC/Chemical Name

(6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChl Key

ZAIPMKNFIOOWCQ-UEKVPHQBSA-N

InChl Code

InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/27447;

3D Conformer.

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