AZLOCILLIN SODIUM
Azlocillin is a penicillin antibiotic effective against gram-negative bacteria. Benefits include strong antipseudomonal activity. Side effects include rash, diarrhea, and hypersensitivity reactions.
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Product Description
Mechanism of action
Azlocillin is an extended‑spectrum ureidopenicillin that binds to penicillin‑binding proteins (PBPs), inhibiting cross‑linking of peptidoglycan and disrupting bacterial cell‑wall synthesis. It exhibits strong activity against Pseudomonas aeruginosa and many Gram‑negative bacilli.
Benefits and advantages
Used in beta‑lactamase research, bacterial membrane‑permeability studies, efflux pump investigations and antipseudomonal drug‑development platforms. Helps model PBP‑binding kinetics and resistance pathways.
Side effects and risks
Potential allergic reactions, GI upset and rare hepatic disturbances. Laboratory use must follow antimicrobial containment protocols.
Datasheet
| Molecular Formula | C20H23N5NaO7S2 |
|---|---|
| Molecular Weight | 483.5 g/mol |
| CAS Number | 37091-65-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Azlocillin sodium salt; AZLOCILLIN SODIUM; 37091-65-9; Sodium azlocillin; Monosodium azlocillin |
| IUPAC/Chemical Name | sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| InChl Key | UVOCNBWUHNCKJM-XFAPPKAWSA-M |
| InChl Code | InChI=1S/C20H23N5O6S.Na/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30;/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29);/q;+1/p-1/t11-,12-,13+,16-;/m1./s1 |
| References |
3D Conformer.
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