AZLOCILLIN SODIUM

Azlocillin is a penicillin antibiotic effective against gram-negative bacteria. Benefits include strong antipseudomonal activity. Side effects include rash, diarrhea, and hypersensitivity reactions.

SKU: fd27e1b0c12a Category: Tag:

Product Description


Mechanism of action

Azlocillin is an extended‑spectrum ureidopenicillin that binds to penicillin‑binding proteins (PBPs), inhibiting cross‑linking of peptidoglycan and disrupting bacterial cell‑wall synthesis. It exhibits strong activity against Pseudomonas aeruginosa and many Gram‑negative bacilli.

Benefits and advantages

Used in beta‑lactamase research, bacterial membrane‑permeability studies, efflux pump investigations and antipseudomonal drug‑development platforms. Helps model PBP‑binding kinetics and resistance pathways.

Side effects and risks

Potential allergic reactions, GI upset and rare hepatic disturbances. Laboratory use must follow antimicrobial containment protocols.

Datasheet


Molecular Formula

C20H23N5NaO7S2

Molecular Weight

483.5 g/mol

CAS Number

37091-65-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Azlocillin sodium salt; AZLOCILLIN SODIUM; 37091-65-9; Sodium azlocillin; Monosodium azlocillin

IUPAC/Chemical Name

sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChl Key

UVOCNBWUHNCKJM-XFAPPKAWSA-M

InChl Code

InChI=1S/C20H23N5O6S.Na/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30;/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29);/q;+1/p-1/t11-,12-,13+,16-;/m1./s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/23685176;

3D Conformer.

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