VALPRAMIDE

Valpramide is an amide derivative of valproic acid with antimanic and anticonvulsant effects. Side effects include weight gain, tremor, GI upset, and hepatotoxicity. Only GMP materials will be supplied, logistics all according to GDP.

SKU: d6921b7abdcf Category: Tag:

Product Description


Mechanism of Action

VALPRAMIDE exhibits a highdimensional biochemical interaction matrix spanning signallingaxis disruption, catalyticdomain modulation, mitochondrialnetwork recalibration, ionflux redistribution, cytoskeletalarchitecture remodelling, membranepotential rebalancing and transcriptionfactor pathway restructuring. Its molecular topology supports interaction with catalytic residues, allosteric regulators, transmembrane helices, nucleotidebinding pockets, redoxbuffer modules and polymeric scaffolding complexes, enabling wideband influence across metabolic, structural, genomic and electrophysiological domains.

Mechanistically, VALPRAMIDE may reshape phosphorylation maps across ERK/MAPK/JNK/p38 axes, alter PI3KAKT survivalbias, modulate Gprotein coupling geometry, redistribute Ca²⁺ microdomain waveforms, adjust IP/DAG signalling topology and recalibrate cAMPPKA amplitude. Mitochondrial impacts include ETCcomplex rebalancing, ATP/ADP cycle modulation, ROSthreshold displacement, mitochondrial membranepotential polarity shifts and crossorganelle stress signalling.

HighPrecision

  • Kinomescale interference & catalyticcascade modelling
  • Highresolution docking & conformationalflow prediction
  • UPR/ERstress & autophagy/mitophagy integration networks
  • Full multiomics reconstruction (RNAseq, proteomics, phosphoproteomics, metabolomics)
  • Cytoskeletal forcemapping & polymer turnover dynamics
  • Cellfate modelling: apoptosis, necroptosis, ferroptosis, parthanatos
  • AIdriven SAR/QSAR predictive simulation

Toxicodynamics & Cellular Hazard Spectrum

  • Excessive ROS accumulation & antioxidantbuffer collapse
  • Mitochondrial fragmentation or ETC suppression
  • Hyperdisruption of Na⁺/K⁺/Ca²⁺ ionicgradients
  • Cytoskeletal degradation & membrane-integrity failure
  • Inflammatory masterswitch activation (NF-κB/STAT/IRF)
  • Multiaxis programmed-cell-death induction
  • Epigenetic drift across methylation & acetylation layers

For expert laboratory research only not intended for biological use.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C8H17NO

Molecular Weight

143.23 g/mol

CAS Number

2430-27-5

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Valpromide; 2-PROPYLPENTANAMIDE; 2430-27-5; Depamide; 2-Propylvaleramide

IUPAC/Chemical Name

2-propylpentanamide

InChl Key

OMOMUFTZPTXCHP-UHFFFAOYSA-N

InChl Code

InChI=1S/C8H17NO/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H2,9,10)

References

https://pubchem.ncbi.nlm.nih.gov/compound/71113;

3D Conformer.

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