URIDINE 5 TRIPHOSPHATE TRISODIUM SALT

Uridine 5triphosphate trisodium is a nucleotide involved in RNA synthesis and cellular metabolism, used in research and metabolic formulations. Side effects may include flushing, headache, GI discomfort, and rare hypersensitivity. Only GMP materials will be supplied, logistics all according to GDP.

Product Description


Mechanism of Action

URIDINE 5 TRIPHOSPHATE TRISODIUM SALT displays a highdimensional biochemical interaction profile, integrating catalyticdomain modulation, multiaxis signalling interference, mitochondrialnetwork recalibration, ionflux redistribution, membranepotential rebalancing, cytoskeletal remodelling, redoxequilibrium restructuring and transcriptionfactor pathway reprogramming. Its molecular topology supports interaction with catalytic residues, allosteric microdomains, transmembrane helices, nucleotidebinding pockets, redoxbuffer centres and polymeric scaffolding complexes, enabling wideband influence across metabolic, genomic, structural and electrophysiological layers.

At the signalling level, URIDINE 5 TRIPHOSPHATE TRISODIUM SALT may reconfigure phosphorylation landscapes spanning ERK/MAPK/JNK/p38 and PI3KAKT axes, modulate Gprotein coupling states, reorganise Ca²⁺ microdomain geometry, adjust IP/DAG cascade topology, and recalibrate cAMPPKA amplitude distributions. Mitochondrial effects can include ETCcomplex rebalancing, ATP/ADP flux modulation, ROSthreshold displacement, membranepotential polarity shifts and bidirectional stresssignal integration between ER and mitochondrial compartments.

Advanced

  • Kinomescale catalyticcascade interference mapping
  • Highresolution docking & conformationaltransition simulations
  • UPR/ERstress, mitophagy & autophagicflux network analysis
  • Full multiomics integration (RNAseq, proteomics, phosphoproteomics, metabolomics)
  • Cytoskeletal mechanics & polymerturnover/forcedistribution modelling
  • Cellfate pathway simulations (apoptosis, necroptosis, ferroptosis, parthanatos)
  • AIdriven SAR/QSAR pipelines for compoundperformance prediction

Toxicodynamics & Hazard Spectrum

  • Rapid ROS escalation & antioxidantbuffer saturation
  • Mitochondrial fragmentation or ETCaxis suppression
  • Severe Na⁺/K⁺/Ca²⁺ ionic-flux destabilisation
  • Cytoskeletal depolymerisation & membrane-integrity loss
  • Hyperactivation of NF-κB, STAT & IRF inflammatory regulators
  • Induction of multiaxis programmed-cell-death pathways
  • Epigenetic drift including methylation/acetylation imbalance

For expert laboratory research only not intended for biological or therapeutic exposure.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C9H11N2O15P3·3Na

Molecular Weight

586.1 g/mol

CAS Number

19817-92-6

Storage Condition

Store at 28°C

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

DTXSID80859053; 1-(5-O-(Hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)pentofuranosyl)pyrimidine-2,4(1H,3H)-dione; 1-[5-O-(Hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)pentofuranosyl]pyrimidine-2,4(1H,3H)-dione; RefChem:1054522; DTXCID00209738

IUPAC/Chemical Name

Uridine 5€²€‘triphosphate trisodium

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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