UNITHIOL – DMPS

Unithiol (DMPS) is a chelating agent binding arsenic, mercury, and other heavy metals to enhance excretion. Side effects include rash, GI upset, leukopenia, and rare anaphylactoid reactions. Only GMP materials will be supplied, logistics all according to GDP.

SKU: a489c884f903 Category: Tag:

Product Description


Mechanism of Action

UNITHIOL – DMPS demonstrates multilayer biochemical influence across signalling hierarchies, catalyticdomain regulation, mitochondrialnetwork energetics, iongradient stability, membrane electrochemistry, redox equilibrium and transcriptionfactor axis alignment. Its molecular topology enables interaction with catalytic residues, allosteric nodes, hydrophobic receptor microdomains, transmembrane helices, redoxbuffer matrices and cytoskeletal scaffolds, resulting in widespectrum modulation across metabolic, structural, electrophysiological and genomic systems.

Mechanistically, UNITHIOL – DMPS may remodel phosphorylation flux across MAPK/ERK/JNK/p38 pathways, reshape PI3KAKT survival topology, modify Gprotein coupling dynamics, reorganise Ca²⁺ signalling microdomains, influence IP/DAG cascade geometry and adjust cAMPPKA amplitude distributions. Mitochondrial impacts include ETCcomplex rebalancing, ATP/ADP turnover pattern shifts, ROSthreshold displacement, membranepotential polarity modulation and ERmitochondrial stresscrosstalk regulation.

Advanced

  • Kinomescale interference mapping and catalyticcascade simulation
  • Highresolution docking and conformationaltransition modelling
  • UPR/ERstress, autophagymitophagy and organellenetwork integration research
  • Multiomics regulatory reconstruction (RNAseq, phosphoproteomics, metabolomics, proteomics)
  • Cytoskeletal tensionmapping and polymerturnover analysis
  • Cellfate simulations (apoptosis, necroptosis, ferroptosis, parthanatos)
  • Machinelearning SAR/QSAR predictive optimisation

Toxicodynamics & Hazard Profile

  • Accelerated ROS accumulation & antioxidantbuffer saturation
  • Mitochondrial fragmentation or ETCaxis destabilisation
  • Severe Na⁺/K⁺/Ca²⁺ ionic-flux dysregulation
  • Cytoskeletal collapse & membrane-integrity failure
  • Inflammatoryaxis hyperactivation (NF-κB, STAT, IRF pathways)
  • Activation of multiaxis programmed-cell-death pathways
  • Epigenetic methylation/acetylation drift

For expert laboratory research only not intended for biological or therapeutic exposure.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C3H8Na2O4S2

Molecular Weight

172.2 g/mol

CAS Number

40737-98-8

Storage Condition

Store at 28°C

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

IUPAC/Chemical Name

2,3-dimercapto-1-propanesulfonic acid

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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