About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
TIROFIBAN (ID 27686) exerts multi‑axis biochemical modulation involving enzymatic‑cascade interference, receptor‑mediated signalling adjustment, oxidative‑stress balancing, mitochondrial‑respiratory modulation, ion‑channel behaviour influence, cytoskeletal‑architecture modification and transcription‑factor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membrane‑anchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP₃/DAG turnover, cAMP regulation, ATP flux and cellular redox‑state stability.
Benefits & Applications
- Receptor–ligand interaction and docking studies
- Kinase/catalytic pathway profiling
- Mitochondrial ATP/ROS functional modelling
- Multi‑omics integration research
- Cytoskeletal and membrane‑dynamics analysis
- Apoptosis, autophagy and survival‑pathway investigations
- SAR/QSAR modelling and molecular optimisation
Risks & Side Effects
- ROS accumulation and oxidative‑stress imbalance
- Mitochondrial overload or ETC suppression
- Ion‑channel destabilisation (Ca²⁺/Na⁺/K⁺)
- Cytoskeletal disruption and membrane integrity loss
- Dose‑dependent cytotoxicity
- Inflammatory cascade activation
Datasheet
| Molecular Formula | C22H24N2O5S |
|---|---|
| Molecular Weight | 440.6 g/mol |
| CAS Number | 144494-65-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Very slightly soluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | tirofiban; 144494-65-5; Agrastat; tirofibanum; N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine |
| IUPAC/Chemical Name | (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid |
| InChl Key | COKMIXFXJJXBQG-NRFANRHFSA-N |
| InChl Code | InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
