TINIDAZOLE

Tinidazole is an antiprotozoal and antibacterial agent disrupting DNA synthesis, used for giardiasis, trichomoniasis, and anaerobic infections. Side effects include metallic taste, nausea, fatigue, and rare neuropathy.

SKU: fe72f9f7daad Category: Tag:

Product Description


Mechanism of Action

TINIDAZOLE (ID 27681) exerts multi‑axis biochemical modulation involving enzymatic‑cascade interference, receptor‑mediated signalling adjustment, oxidative‑stress balancing, mitochondrial‑respiratory modulation, ion‑channel behaviour influence, cytoskeletal‑architecture modification and transcription‑factor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membrane‑anchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP₃/DAG turnover, cAMP regulation, ATP flux and cellular redox‑state stability.

Benefits & Applications

  • Receptor–ligand interaction and docking studies
  • Kinase/catalytic pathway profiling
  • Mitochondrial ATP/ROS functional modelling
  • Multi‑omics integration research
  • Cytoskeletal and membrane‑dynamics analysis
  • Apoptosis, autophagy and survival‑pathway investigations
  • SAR/QSAR modelling and molecular optimisation

Risks & Side Effects

  • ROS accumulation and oxidative‑stress imbalance
  • Mitochondrial overload or ETC suppression
  • Ion‑channel destabilisation (Ca²⁺/Na⁺/K⁺)
  • Cytoskeletal disruption and membrane integrity loss
  • Dose‑dependent cytotoxicity
  • Inflammatory cascade activation

Datasheet


Molecular Formula

C8H13N3O7S2

Molecular Weight

247.27 g/mol

CAS Number

19387-91-8

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

tinidazole; 19387-91-8; Fasigyn; Trimonase; Fasigin

IUPAC/Chemical Name

1-(2-ethylsulfonylethyl)-2-methyl-5-nitroimidazole

InChl Key

HJLSLZFTEKNLFI-UHFFFAOYSA-N

InChl Code

InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3

References

https://pubchem.ncbi.nlm.nih.gov/compound/5479;

3D Conformer.

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