SOMATOSTATIN

Somatostatin is an endogenous peptide hormone that inhibits GH, insulin, glucagon, and GI secretions. Used diagnostically and for hormone-secreting tumors. Side effects include nausea, steatorrhea, gallstones, and glucose imbalance. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 3a316409620f Category: Tag:

Request a quote now

About MedicaPharma

MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.

Network of over +400 GMP API producers

Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.

Why Choose MedicaPharma

Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations

Product Description


Mechanism of Action

SOMATOSTATIN exhibits a broad and highcomplexity biochemical activity spectrum, modulating hierarchical signalling cascades, deep enzymatic networks, mitochondrial functional architecture, cytoskeletal integrity, transcriptionfactor coordination and multiaxis stressresponse systems. Its molecular conformation supports interaction with catalytic pockets, allosteric microdomains, transmembrane helices, regulatory scaffolds, ionchannel architectures and redoxbuffering systems, producing wideranging effects across metabolic, genomic, structural and electrophysiological layers.

Mechanistically, SOMATOSTATIN may alter phosphorylation topologies, reshape signallingcascade propagation (ERK, JNK, MAPK, PI3KAKT), amplify or suppress secondmessenger concentrations (Ca²⁺, cAMP, IP, DAG), modify mitochondrial membrane polarity, shift ATP/ADP cycling behaviour, regulate ROSleakage thresholds and influence global metabolic flux distribution. Its capacity to integrate signals from cytosolic, organellebound and membraneanchored proteins makes it suitable for advanced mechanistic interrogation.

HighLevel

  • Deep kinomemapping & systemslevel pathwayinterference analysis
  • Structural docking, ligandstability modelling & conformational dynamics
  • Mitochondrialstress analysis including ETC complex modelling
  • UPR, ERstress & integrated autophagy/mitophagy evaluation
  • Multiomics network reconstruction (RNAseq, phosphoproteomics, metabolomics)
  • Membranedynamics and cytoskeletal mechanotransduction studies
  • Advanced cellfate modelling across apoptosis, necroptosis & ferroptosis axes
  • Predictive SAR/QSAR pipelines using machinelearning optimisation

Toxicodynamics & Cellular Risk Spectrum

  • Rapid ROS escalation & antioxidant-system saturation
  • Mitochondrial fragmentation or ETC suppression
  • Severe ionic-flux dysregulation (Ca²⁺, Na⁺, K⁺)
  • Cytoskeletal collapse & membrane-integrity compromise
  • Inflammatory upregulation (NF-κB, STAT, IRF)
  • Activation of programmed-cell-death pathways
  • Epigenetic drift involving methylation & acetylation instability

For expert not for biological or therapeutic exposure.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C76H104N18O19S2

Molecular Weight

1637.9 g/mol

CAS Number

38916-34-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

SOMATOSTATIN; Cyclic Somatostatin; 38916-34-6; Somatostatina; Somatostatine

IUPAC/Chemical Name

(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-37-[[2-[[(2S)-2-aminopropanoyl]amino]acetyl]amino]-13,25,28-tribenzyl-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid

InChl Key

NHXLMOGPVYXJNR-ATOGVRKGSA-N

InChl Code

InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/16129706;

Request a quote now

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download