RIBOFURANOSE

Ribofuranose is a sugar moiety used as a building block for nucleosides and nucleotide analogs. It supports RNA‑based drug development. It is not used therapeutically itself. Exposure risks are minimal but may include irritation or mild GI upset if ingested.

SKU: 72344797a72f Category: Tag:

Product Description


Mechanism of Action

RIBOFURANOSE (ID 27356) engages in multi‑layer biochemical interactions affecting enzyme cascades, receptor‑regulated signalling, oxidative‑stress systems, mitochondrial respiration, ion‑channel dynamics, cytoskeletal mechanics and transcription‑factor pathway coordination. Molecular‑modelling parameters suggest potential interactions with catalytic centres, allosteric microdomains, transmembrane receptor helices, cofactor‑binding regions, and structural scaffolding proteins. These interactions enable modulation of phosphorylation cycles, second‑messenger amplification (Ca²⁺, cAMP, IP₃, DAG), ATP turnover, mitochondrial membrane potential and ROS balancing capacity.

Benefits and Applications

  • Receptor‑ligand affinity mapping and molecular docking
  • Enzyme‑kinetic pathway modelling and catalytic‑flux analysis
  • Mitochondrial bioenergetics profiling and redox‑state research
  • Multi‑omics studies (transcriptomics, metabolomics, proteomics)
  • Cytoskeletal architecture analysis and membrane‑dynamics modelling
  • Apoptosis, necroptosis, autophagy and ferroptosis pathway assays
  • SAR and QSAR‑driven molecular optimisation
  • Pharmacodynamic and mechanistic dose‑response modelling

Risks & Side Effects

  • Oxidative imbalance and ROS escalation
  • Mitochondrial overload or suppression of respiratory complexes
  • Ion‑channel destabilisation (Na⁺/K⁺/Ca²⁺)
  • Unintended receptor cross‑talk
  • Cytoskeletal destabilisation
  • Dose‑dependent cytotoxicity or programmed‑cell‑death activation
  • Inflammatory transcriptional activation (NF‑κB, JNK, MAPK)

Datasheet


Molecular Formula

C5H10O5

Molecular Weight

150.13 g/mol

CAS Number

613-83-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

D-ribofuranose; 613-83-2; DTXSID201317333; RefChem:937744; GlyTouCan:G31080DL

IUPAC/Chemical Name

(3R,4S,5R)-5-(hydroxymethyl)oxolane-2,3,4-triol

InChl Key

HMFHBZSHGGEWLO-SOOFDHNKSA-N

InChl Code

InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/5779;

3D Conformer.

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