About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
RIBAVIRIN (ID 27353) engages in multi‑layer biochemical interactions affecting enzyme cascades, receptor‑regulated signalling, oxidative‑stress systems, mitochondrial respiration, ion‑channel dynamics, cytoskeletal mechanics and transcription‑factor pathway coordination. Molecular‑modelling parameters suggest potential interactions with catalytic centres, allosteric microdomains, transmembrane receptor helices, cofactor‑binding regions, and structural scaffolding proteins. These interactions enable modulation of phosphorylation cycles, second‑messenger amplification (Ca²⁺, cAMP, IP₃, DAG), ATP turnover, mitochondrial membrane potential and ROS balancing capacity.
Benefits and Applications
- Receptor‑ligand affinity mapping and molecular docking
- Enzyme‑kinetic pathway modelling and catalytic‑flux analysis
- Mitochondrial bioenergetics profiling and redox‑state research
- Multi‑omics studies (transcriptomics, metabolomics, proteomics)
- Cytoskeletal architecture analysis and membrane‑dynamics modelling
- Apoptosis, necroptosis, autophagy and ferroptosis pathway assays
- SAR and QSAR‑driven molecular optimisation
- Pharmacodynamic and mechanistic dose‑response modelling
Risks & Side Effects
- Oxidative imbalance and ROS escalation
- Mitochondrial overload or suppression of respiratory complexes
- Ion‑channel destabilisation (Na⁺/K⁺/Ca²⁺)
- Unintended receptor cross‑talk
- Cytoskeletal destabilisation
- Dose‑dependent cytotoxicity or programmed‑cell‑death activation
- Inflammatory transcriptional activation (NF‑κB, JNK, MAPK)
Datasheet
| Molecular Formula | C8H12N4O5 |
|---|---|
| Molecular Weight | 244.20 g/mol |
| CAS Number | 36791-04-5 |
| Storage Condition | Commercially available ribavirin powder for inhalation solution should be stored in tight containers in a dry place at 15-25 °C. … Ribavirin inhalation solutions contain no preservatives and are stable for 24 hours when stored under sterile conditions at a room temperature of 20-30 °C. … Ribavirin capsules or tablets should be stored at 25 °C, but may be exposed temperatures ranging from 15-30 °C. Ribavirin oral solution should be stored at 2-8 °C or at 25 °C, but may be exposed to temperatures ranging from 15-30 °C. |
| Solubility | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | ribavirin; 36791-04-5; Tribavirin; Rebetol; Virazole |
| IUPAC/Chemical Name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide |
| InChl Key | IWUCXVSUMQZMFG-AFCXAGJDSA-N |
| InChl Code | InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
