RESORCINOL

Resorcinol is a topical antiseptic and keratolytic used for dermatitis, acne, and seborrhea. Side effects include redness, peeling, irritation, and, with excessive use, systemic toxicity.

SKU: e0f8eed213e7 Category: Tag:

Product Description


Mechanism of Action

RESORCINOL (ID 27345) engages in multi‑layer biochemical interactions affecting enzyme cascades, receptor‑regulated signalling, oxidative‑stress systems, mitochondrial respiration, ion‑channel dynamics, cytoskeletal mechanics and transcription‑factor pathway coordination. Molecular‑modelling parameters suggest potential interactions with catalytic centres, allosteric microdomains, transmembrane receptor helices, cofactor‑binding regions, and structural scaffolding proteins. These interactions enable modulation of phosphorylation cycles, second‑messenger amplification (Ca²⁺, cAMP, IP₃, DAG), ATP turnover, mitochondrial membrane potential and ROS balancing capacity.

Benefits and Applications

  • Receptor‑ligand affinity mapping and molecular docking
  • Enzyme‑kinetic pathway modelling and catalytic‑flux analysis
  • Mitochondrial bioenergetics profiling and redox‑state research
  • Multi‑omics studies (transcriptomics, metabolomics, proteomics)
  • Cytoskeletal architecture analysis and membrane‑dynamics modelling
  • Apoptosis, necroptosis, autophagy and ferroptosis pathway assays
  • SAR and QSAR‑driven molecular optimisation
  • Pharmacodynamic and mechanistic dose‑response modelling

Risks & Side Effects

  • Oxidative imbalance and ROS escalation
  • Mitochondrial overload or suppression of respiratory complexes
  • Ion‑channel destabilisation (Na⁺/K⁺/Ca²⁺)
  • Unintended receptor cross‑talk
  • Cytoskeletal destabilisation
  • Dose‑dependent cytotoxicity or programmed‑cell‑death activation
  • Inflammatory transcriptional activation (NF‑κB, JNK, MAPK)

Datasheet


Molecular Formula

C6H6O2

Molecular Weight

110.11 g/mol

CAS Number

108-46-3

Storage Condition

Separated from incompatible materials and food and feedstuffs.

Solubility

greater than or equal to 100 mg/mL at 65.3 °F (NTP, 1992)

Purity

Purity information is available upon request (COA).

Synonym

resorcinol; 108-46-3; benzene-1,3-diol; 1,3-Benzenediol; Resorcin

IUPAC/Chemical Name

benzene-1,3-diol

InChl Key

GHMLBKRAJCXXBS-UHFFFAOYSA-N

InChl Code

InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H

References

https://pubchem.ncbi.nlm.nih.gov/compound/5054;

3D Conformer.

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