PIPROZOLINE

Piproxoline is an antihistamine with sedative and anticholinergic properties used for allergic rhinitis. Benefits include reduced itching, sneezing, and rhinorrhea. Side effects include drowsiness, dizziness, dry mouth, and paradoxical agitation in children.

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Product Description


Scientific Overview

PIPROZOLINE (ID 27148) is a research‑grade biochemical compound used for advanced analytical, mechanistic and structural studies. It is often applied in laboratory environments requiring precise molecular behaviour, controlled pathway modulation and high‑fidelity reproducibility. The compound interacts with multiple biochemical systems depending on formulation, cell type and experimental conditions.

Mechanism of Action

Although the exact mechanism may vary by experimental model, PIPROZOLINE typically exhibits activity involving:

  • Enzymatic pathway modulation through reversible or irreversible interaction with catalytic sites
  • Potential receptor‑level signaling effects influencing intracellular second messengers
  • Alterations in redox balance and oxidative‑stress handling systems
  • Mitochondrial functional modulation, including effects on ATP turnover and respiratory‑chain efficiency
  • Influence on transcriptional behaviour, gene‑expression clusters and regulatory protein networks
  • Possible interaction with cytoskeletal structures affecting cellular stability and mechanical signaling

These combined effects make the compound suitable for multi‑axis biochemical research.

Benefits and Applications

PIPROZOLINE is commonly used for:

  • Pathway validation and mechanistic investigation
  • Binding‑affinity studies and structural modelling
  • Metabolic‑flux analysis and mitochondrial‑function profiling
  • Redox and oxidative‑stress research environments
  • Cytoskeletal and membrane‑dynamic studies
  • Signal‑transduction mapping across diverse biological systems

Risks and Safety Considerations

Potential risks associated with laboratory exposure include:

  • Oxidative imbalance or ROS accumulation
  • Mitochondrial stress or functional suppression at high concentrations
  • Unintended receptor or enzyme cross‑interaction
  • Cytoskeletal destabilization or membrane disturbance
  • Dose‑dependent cytotoxicity under prolonged exposure

Handle only with appropriate laboratory biosafety protocols.

Datasheet


Molecular Formula

C14H22N2O3S

Molecular Weight

298.40 g/mol

CAS Number

63250-48-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

PIPROZOLIN; Probilin; Coleflux; Secrebil; Piprozolina

IUPAC/Chemical Name

ethyl (2Z)-2-(3-ethyl-4-oxo-5-piperidin-1-yl-1,3-thiazolidin-2-ylidene)acetate

InChl Key

UAXYBJSAPFTPNB-KHPPLWFESA-N

InChl Code

InChI=1S/C14H22N2O3S/c1-3-16-11(10-12(17)19-4-2)20-14(13(16)18)15-8-6-5-7-9-15/h10,14H,3-9H2,1-2H3/b11-10-

References

https://pubchem.ncbi.nlm.nih.gov/compound/5911905;

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