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Product Description
Mechanism of Action
PHENYLEPHRINE HCL (ID 27094) demonstrates a broad, multi‑layer biochemical activity profile affecting enzyme‑driven catalytic pathways, receptor‑regulated signalling systems, mitochondrial bioenergetics, redox‑state equilibrium, ion‑channel behaviour, cytoskeletal integrity and transcription‑factor regulatory networks. Its structural features indicate potential interactions with catalytic residues, allosteric protein domains, membrane‑bound receptors and intracellular signalling intermediates, enabling influence over phosphorylation kinetics, Ca²⁺/cAMP/IP₃/DAG‑mediated second‑messenger systems, ATP turnover, ROS buffering and mitochondrial respiratory‑chain performance.
Depending on concentration and biological conditions, PHENYLEPHRINE HCL may modulate metabolic flux distribution, alter mitochondrial membrane potential, influence chromatin accessibility, impact vesicular trafficking dynamics and reshape gene‑expression patterns relevant to survival, inflammation, apoptosis, autophagy, metabolic adaptation and redox‑stress response.
Benefits and Advantages
This compound is widely used across advanced biochemical, pharmacological and mechanistic research domains, including:
- Receptor–ligand interaction studies and affinity‑mapping
- Enzyme‑kinetic pathway deconstruction and catalytic‑domain profiling
- Mitochondrial‑function analysis and ATP‑flux/oxidative‑stress modelling
- Multi‑omics integration (transcriptomics, metabolomics, proteomics, phosphoproteomics)
- Cytoskeletal‑structure and membrane‑dynamics research
- Autophagy, apoptosis, necroptosis and ferroptosis signalling investigations
- SAR (structure–activity relationship) profiling and compound‑optimisation workflows
- Pharmacodynamic modelling, threshold‑activation mapping and dose–response scaling
Side Effects and Risks
Laboratory‑observed or predicted risks include:
- Oxidative imbalance and excessive ROS accumulation
- Mitochondrial overload or respiratory‑chain suppression
- Dysregulation of Na⁺/K⁺/Ca²⁺ ion‑channel homeostasis
- Unintended receptor cross‑talk or inhibitory interference
- Cytoskeletal destabilisation and membrane‑integrity disruption
- Dose‑dependent cytotoxicity with apoptosis/autophagy activation
- Transcriptional instability or epigenetic disturbance
- Inflammatory signalling activation via NF‑κB, MAPK or JNK pathways
Use strictly within controlled laboratory environments under appropriate biosafety protocols.
Datasheet
| Molecular Formula | C9H13NO2·HCl |
|---|---|
| Molecular Weight | 203.66 g/mol |
| CAS Number | 61-76-7 |
| Storage Condition | Store below 40 °C (104 °F), preferably between 15 and 30 °C (59 and 86 °F), unless otherwise specified by manufacturer. Store in a tight, light-resistant container if not more than 15 mL size. Protect from freezing. |
| Solubility | greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | PHENYLEPHRINE HYDROCHLORIDE; 61-76-7; Phenylephrine HCl; Biomydrin; Mydfrin |
| IUPAC/Chemical Name | 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride |
| InChl Key | OCYSGIYOVXAGKQ-FVGYRXGTSA-N |
| InChl Code | InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1 |
| References |
3D Conformer.
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