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Product Description
Mechanism of Action
OXYFEDRINE (ID 26998) exhibits a multidimensional biochemical activity profile involving modulation of enzyme-catalyzed pathways, receptor-mediated intracellular signaling, ion-channel regulation, mitochondrial bioenergetics, oxidative-stress balancing, membrane dynamics, and transcription-factor orchestration. Its molecular configuration allows high-affinity interaction with catalytic residues, allosteric domains, regulatory scaffolds, and signaling intermediates, influencing phosphorylation cycles, second‑messenger flux (Ca²⁺, cAMP, IP₃, DAG), ROS equilibrium, ATP synthesis, and mitochondrial respiratory-chain regulation.
Depending on dose, exposure duration, and cell type, OXYFEDRINE can modify chromatin accessibility, metabolic flux routing, vesicular trafficking, cytoskeletal structure, and gene-expression clusters associated with survival, inflammation, apoptosis, autophagy, and metabolic adaptation.
Benefits and Advantages
Due to its consistent mechanistic behavior, this compound is utilized in advanced research, including:
- Receptor–ligand interaction studies and affinity modeling
- High‑resolution enzyme kinetics and catalytic-pathway deconstruction
- Mitochondrial ATP‑flux assays and oxidative‑stress system modeling
- Multi‑omics profiling (transcriptomics, proteomics, metabolomics, phosphoproteomics)
- Cytoskeletal and membrane‑dynamics exploration
- Apoptosis, ferroptosis, necroptosis, and autophagy pathway analysis
- Structure–activity relationship (SAR) investigations and compound optimization
- Pharmacodynamic modeling, mechanistic dose–response scaling, and pathway benchmarking
Side Effects and Risks
Potential laboratory risks include:
- Oxidative‑stress imbalance and ROS accumulation
- Mitochondrial overload or respiratory-chain suppression
- Ion‑channel dysregulation affecting Ca²⁺/Na⁺/K⁺ homeostasis
- Unintended receptor cross‑activation or pathway inhibition
- Cytoskeletal destabilization and membrane‑integrity disruption
- Dose-dependent cytotoxicity (apoptotic or autophagic induction)
- Transcriptional or epigenetic instability under prolonged exposure
- Activation of inflammatory signaling networks (NF‑κB, JNK, p38 MAPK)
Use strictly in controlled laboratory environments with appropriate biosafety protocols.
Datasheet
| Molecular Formula | C19H23NO3 |
|---|---|
| Molecular Weight | 313.4 g/mol |
| CAS Number | 15687-41-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | OXYFEDRINE; 15687-41-9; Oxifedrina; Oxyfedrinum; (-)-oxyfedrine |
| IUPAC/Chemical Name | 3-[[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-(3-methoxyphenyl)propan-1-one |
| InChl Key | GDYUVHBMFVMBAF-LIRRHRJNSA-N |
| InChl Code | InChI=1S/C19H23NO3/c1-14(19(22)15-7-4-3-5-8-15)20-12-11-18(21)16-9-6-10-17(13-16)23-2/h3-10,13-14,19-20,22H,11-12H2,1-2H3/t14-,19-/m0/s1 |
| References |
3D Conformer.
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