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Product Description
Mechanism of Action
MIVACURIUM CHLORIDE exhibits a deeply layered biochemical action profile involving coordinated modulation of enzyme-driven catalytic cascades, receptor-mediated signalling processes, intracellular ion dynamics, mitochondrial bioenergetics, membrane-potential stability and transcription-factor pathway regulation. Its molecular architecture supports high-affinity interaction with both catalytic and regulatory protein domains. These interactions allow the compound to influence phosphorylationdephosphorylation cycles, reactive oxygen species (ROS) equilibrium, ATP turnover, calcium flux, and mitochondrial redox-state balance. In many experimental systems, MIVACURIUM CHLORIDE contributes to structural-protein reorganisation, cytoskeletal tension modulation and vesicular transport behaviour.
The compound may also affect chromatin accessibility and epigenetic markers, shifting transcriptional activity across multiple gene clusters involved in stress adaptation, metabolic steering and survival signalling. Such multi-dimensional mechanistic behaviour underlies its utility in complex research models.
Benefits and Advantages
MIVACURIUM CHLORIDE is suitable for a wide range of advanced laboratory , including:
- Detailed receptorligand interaction mapping and affinity-modelling
- High-resolution enzymatic kinetic analysis and catalytic cascade mapping
- Mitochondrial-function assays, ATP-flux modelling and oxidative-stress monitoring
- Multi-omics systems: transcriptomics, proteomics, metabolomics and phosphoproteomics
- Cytoskeletal-dynamics research including actintubulin remodelling and mechanical signalling
- Apoptosis, necroptosis, ferroptosis and autophagy signalling studies
- SAR (structureactivity relationship) development and molecular-performance optimisation
- Advanced pharmacodynamic simulations and doseresponse mechanistic modelling
Side Effects and Risks
Potential risks associated with MIVACURIUM CHLORIDE include:
- Oxidative-stress imbalance leading to ROS accumulation
- Mitochondrial overactivation or suppression of respiratory-chain complexes
- Ion-channel dysregulation affecting Ca²⁺/Na⁺/K⁺ homeostasis
- Unintended receptor cross-activation or inhibition
- Cytoskeletal destabilisation and membrane-integrity compromise
- Dose-dependent cytotoxicity, apoptosis, autophagy or metabolic-collapse signalling
- Activation of inflammatory transcriptional programmes (e.g., NF-κB, p38 MAPK, JNK)
Prolonged exposure or excessive concentration may trigger transcriptional rewiring, altered metabolic routing, organelle stress responses, or epigenetic instability. Handle only under controlled laboratory conditions with appropriate biosafety procedures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C58H82Cl2N2O10 |
|---|---|
| Molecular Weight | 1100.2 g/mol |
| CAS Number | 106861-44-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | MIVACURIUM CHLORIDE; 106861-44-3; Mivacron; Cloruro de mivacurio; Chlorure de mivacurium |
| IUPAC/Chemical Name | bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate dichloride |
| InChl Key | WMSYWJSZGVOIJW-ONUALHDOSA-L |
| InChl Code | InChI=1S/C58H80N2O14.2ClH/c1-59(25-21-41-35-47(63-3)49(65-5)37-43(41)45(59)29-39-31-51(67-7)57(71-11)52(32-39)68-8)23-17-27-73-55(61)19-15-13-14-16-20-56(62)74-28-18-24-60(2)26-22-42-36-48(64-4)50(66-6)38-44(42)46(60)30-40-33-53(69-9)58(72-12)54(34-40)70-10;;/h13-14,31-38,45-46H,15-30H2,1-12H3;2*1H/q+2;;/p-2/b14-13+;;/t45-,46-,59?,60?;;/m1../s1 |
| References |
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