About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
METHENAMINE MANDELATE (ID 26684) demonstrates an extensive, multi‑axis biochemical activity profile involving coordinated modulation of receptor‑mediated signalling, enzyme‑regulated catalytic cascades, mitochondrial bioenergetics, intracellular ion regulation, and transcriptomic pathway dynamics. Its physicochemical properties support high‑affinity interactions with both catalytic and regulatory protein domains, enabling interference with phosphorylation–dephosphorylation cycles, second‑messenger turnover (cAMP, IP₃, DAG, Ca²⁺), and redox‑equilibrium systems.
In cellular environments, METHENAMINE MANDELATE may influence mitochondrial membrane potential, ATP synthesis efficiency, ROS generation and antioxidant neutralisation capacity. In addition, structural‑protein interactions can modify cytoskeletal arrangement, impacting cell motility, vesicular trafficking, and mechanical signalling. The compound may further modulate chromatin accessibility, transcription factor binding profiles, epigenetic markers, and gene‑expression stability.
Benefits and Advantages
Because of its reproducible biochemical footprint, METHENAMINE MANDELATE is an important tool across advanced research domains, including:
- Detailed receptor‑ligand binding analysis and structural docking validation
- High‑definition enzyme kinetics and catalytic‑domain pathway mapping
- Mitochondrial respiration modelling, ATP‑flux analysis and oxidative‑stress pathway evaluation
- Transcriptomic, proteomic and metabolomic integration studies for full‑pathway profiling
- Apoptosis, necroptosis and autophagy‑related signalling research
- Cytoskeletal‑dynamics studies involving actin, tubulin and intermediate filaments
- High‑resolution SAR (structure–activity relationship) investigations for molecular optimisation
- Pharmacodynamic modelling for dose‑response, threshold‑activation and mechanistic benchmarking
Side Effects and Risks
Potential risks include:
- Redox imbalance and excessive ROS accumulation
- Mitochondrial overload or respiratory‑chain suppression
- Transcriptional pathway disruption or epigenetic instability
- Interference with ion‑channel behaviour and calcium‑handling regulation
- Cytoskeletal destabilisation and impaired membrane integrity
- Dose‑dependent cytotoxicity, apoptosis or autophagy induction
- Activation of inflammatory signalling cascades such as NF‑κB, JNK, or p38
Extended exposure or elevated dosing may trigger metabolic rewiring, organelle stress responses, or long‑term alterations in cellular signalling architecture. Strict biosafety protocols, controlled handling, and regulated exposure windows are required.
Datasheet
| Molecular Formula | C14H16N4O3 |
|---|---|
| Molecular Weight | 292.33 g/mol |
| CAS Number | 587-23-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | METHENAMINE MANDELATE; 587-23-5; Hexydaline; Hexamine mandelate; 695N30CINR |
| IUPAC/Chemical Name | 2-hydroxy-2-phenylacetic acid;1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane |
| InChl Key | UXNFIJPHRQEWRQ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H8O3.C6H12N4/c9-7(8(10)11)6-4-2-1-3-5-6;1-7-2-9-4-8(1)5-10(3-7)6-9/h1-5,7,9H,(H,10,11);1-6H2 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
