MESCOMINE

Mescomine is a stimulant compound with sympathomimetic activity, increasing alertness and energy. Benefits include enhanced wakefulness. Side effects may include increased heart rate, anxiety, tremors, and insomnia.

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Product Description


Mechanism of Action

MESCOMINE (ID 26659) displays a broad and multi‑axis biochemical interaction profile characterised by modulation of enzymatic networks, receptor‑mediated signalling, intracellular ion regulation, mitochondrial bioenergetics and transcriptional pathway governance. Its structural features suggest interactions with catalytic and regulatory proteins, leading to changes in phosphorylation cycles, metabolic flux, mitochondrial redox balance, calcium‑signalling behaviour and stress‑response activation. Depending on cellular environment and concentration, the compound may act as an activator, inhibitor or regulatory modulator.

Benefits and Advantages

This compound supports a wide range of research applications, including:

  • Receptor–ligand affinity profiling and binding‑site mapping
  • Enzyme‑cascade modelling and catalytic‑domain interaction studies
  • Mitochondrial‑function assays, oxidative‑stress evaluation and metabolic‑flux tracking
  • Transcriptomic, proteomic and metabolomic investigation for pathway mapping
  • Apoptosis / autophagy pathway research and cellular‑stress modelling
  • High‑resolution mechanism‑of‑action studies and SAR exploration

Side Effects and Risks

Potential risks include oxidative imbalance, mitochondrial overload, ion‑channel dysregulation, receptor cross‑talk, cytoskeletal disruption and dose‑dependent cytotoxicity. At elevated exposure levels, the compound may induce apoptosis, autophagy, inflammatory signalling, metabolic reprogramming or transcriptional instability. Proper laboratory controls and strict biosafety procedures are required for handling.

Datasheet


Molecular Formula

C18H24N2O7

Molecular Weight

380.4 g/mol

CAS Number

6106-46-3

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

>57.1 [ug/mL] (The mean of the results at pH 7.4)

Purity

Purity information is available upon request (COA).

Synonym

Methscopolamine nitrate; Hyoscine methonitrate; Skopolate; Viscope; Skopyl

IUPAC/Chemical Name

[(1R,2R,4S,5S)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate nitrate

InChl Key

BSQIVYOSLFLSGE-OZVSTBQFSA-N

InChl Code

InChI=1S/C18H24NO4.NO3/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;2-1(3)4/h3-7,12-17,20H,8-10H2,1-2H3;/q+1;-1/t12?,13-,14-,15+,16-,17+;/m1./s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/657297;

3D Conformer.

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