MEMANTINE BASE

Memantine base exerts the same neuroprotective NMDA‑modulating effects as the hydrochloride form. Side effects may include confusion, dizziness, and increased blood pressure.

SKU: 4a7ef1cbaf6d Category: Tag:

Product Description


Mechanism of Action

MEMANTINE BASE (ID 26636) displays a broad and multi‑axis biochemical interaction profile characterised by modulation of enzymatic networks, receptor‑mediated signalling, intracellular ion regulation, mitochondrial bioenergetics and transcriptional pathway governance. Its structural features suggest interactions with catalytic and regulatory proteins, leading to changes in phosphorylation cycles, metabolic flux, mitochondrial redox balance, calcium‑signalling behaviour and stress‑response activation. Depending on cellular environment and concentration, the compound may act as an activator, inhibitor or regulatory modulator.

Benefits and Advantages

This compound supports a wide range of research applications, including:

  • Receptor–ligand affinity profiling and binding‑site mapping
  • Enzyme‑cascade modelling and catalytic‑domain interaction studies
  • Mitochondrial‑function assays, oxidative‑stress evaluation and metabolic‑flux tracking
  • Transcriptomic, proteomic and metabolomic investigation for pathway mapping
  • Apoptosis / autophagy pathway research and cellular‑stress modelling
  • High‑resolution mechanism‑of‑action studies and SAR exploration

Side Effects and Risks

Potential risks include oxidative imbalance, mitochondrial overload, ion‑channel dysregulation, receptor cross‑talk, cytoskeletal disruption and dose‑dependent cytotoxicity. At elevated exposure levels, the compound may induce apoptosis, autophagy, inflammatory signalling, metabolic reprogramming or transcriptional instability. Proper laboratory controls and strict biosafety procedures are required for handling.

Datasheet


Molecular Formula

C12H21N

Molecular Weight

179.3 g/mol

CAS Number

19982-08-2

Storage Condition

Store at 2-8°C

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

memantine; 19982-08-2; 3,5-dimethyladamantan-1-amine; 1-Amino-3,5-dimethyladamantane; Memantina

IUPAC/Chemical Name

1-amino-3,5-dimethyladamantane

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download