MELOXICAM

Meloxicam is an oxicam NSAID preferentially inhibiting COX2 to reduce pain and inflammation. Benefits include effective relief in arthritis. Side effects include GI irritation, ulcer risk, renal effects, and edema. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 8a670d01e9db Category: Tag:

Product Description


Mechanism of Action

MELOXICAM exhibits a multilayered biochemical interaction profile involving modulation of enzyme cascades, receptorregulated signalling, mitochondrial bioenergetics, redoxstate equilibrium, membranepotential dynamics and transcriptionfactor activation. Depending on concentration and cellular context, the compound can influence phosphorylation cycles, alter calcium signalling thresholds, disrupt or stabilise cytoskeletal structures, and reprogram metabolic flux pathways.

Benefits and Advantages

This compound is widely used in advanced mechanistic research, including:

  • Receptorligand interaction analysis and allostericbinding studies
  • Enzymekinetic mapping and catalyticdomain investigation
  • Mitochondrialfunction, ROSbalance and redoxmodulation assays
  • Transcriptomic, proteomic and metabolomic profiling
  • Cellularstress signalling, apoptosis/autophagy modelling and membranedynamics studies
  • Pharmacodynamic simulation, SAR evaluation and earlystage compound screening

Side Effects and Risks

Possible risks include mitochondrial overload, oxidativestress imbalance, ionchannel disruption, metabolic pathway misregulation, receptor crosstalk, and dosedependent cytotoxicity. At higher exposure, apoptosis, autophagy, transcriptional destabilisation or inflammationpathway activation may occur. Use only with strict laboratory safety procedures.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C14H13N3O4S2

Molecular Weight

351.4 g/mol

CAS Number

71125-38-7

Storage Condition

Store at 25 °C (77 °F); excursions permitted to 15-30 °C (59-86 °F).

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

meloxicam; 71125-38-7; Mobic; Metacam; Mobicox

IUPAC/Chemical Name

4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide

InChl Key

ZRVUJXDFFKFLMG-UHFFFAOYSA-N

InChl Code

InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)

References

https://pubchem.ncbi.nlm.nih.gov/compound/54677470;

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download