About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
MEDAMINE exhibits a multilayered biochemical interaction profile involving modulation of enzyme cascades, receptorregulated signalling, mitochondrial bioenergetics, redoxstate equilibrium, membranepotential dynamics and transcriptionfactor activation. Depending on concentration and cellular context, the compound can influence phosphorylation cycles, alter calcium signalling thresholds, disrupt or stabilise cytoskeletal structures, and reprogram metabolic flux pathways.
Benefits and Advantages
This compound is widely used in advanced mechanistic research, including:
- Receptorligand interaction analysis and allostericbinding studies
- Enzymekinetic mapping and catalyticdomain investigation
- Mitochondrialfunction, ROSbalance and redoxmodulation assays
- Transcriptomic, proteomic and metabolomic profiling
- Cellularstress signalling, apoptosis/autophagy modelling and membranedynamics studies
- Pharmacodynamic simulation, SAR evaluation and earlystage compound screening
Side Effects and Risks
Possible risks include mitochondrial overload, oxidativestress imbalance, ionchannel disruption, metabolic pathway misregulation, receptor crosstalk, and dosedependent cytotoxicity. At higher exposure, apoptosis, autophagy, transcriptional destabilisation or inflammationpathway activation may occur. Use only with strict laboratory safety procedures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C11H13N3O2 |
|---|---|
| Molecular Weight | 191.19 g/mol |
| CAS Number | 10605-21-7 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. |
| Solubility | less than 1 mg/mL at 70 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Carbendazim; 10605-21-7; Mecarzole; Bavistin; Carbendazole |
| IUPAC/Chemical Name | methyl N-(1H-benzimidazol-2-yl)carbamate |
| InChl Key | TWFZGCMQGLPBSX-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
