LEVOSULPIRIDE

Levosulpiride is a dopamine D2 antagonist enhancing GI motility and mood. Benefits include relief in dyspepsia and depression. Side effects include hyperprolactinemia, weight gain, and drowsiness. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 8b0d49c57f96 Category: Tag:

Product Description


Mechanism of Action

LEVOSULPIRIDE demonstrates a highcomplexity biochemical profile involving modulation of receptor systems, enzymeregulated metabolic pathways, mitochondrial performance, intracellular ion dynamics and transcriptionlevel regulation. Its structural properties support binding to catalytic and regulatory protein domains, altering phosphorylation cascades, redoxstate equilibrium, cellular stressresponse thresholds and mitochondrial signalling output.

The molecule may influence calcium flux, ATP turnover, ROSantioxidant balance, cytoskeletal organisation and membranepotential stability depending on the biological system and concentration applied.

Benefits and Advantages

Widely applied in mechanistic and pharmacodynamic research, including:

  • Receptorligand interaction analysis and affinity profiling
  • Enzymekinetic and catalyticpathway investigations
  • Mitochondrialfunction, metabolicflux and oxidativestress studies
  • Multiomics research: transcriptomics, proteomics and metabolomics
  • Cellstress signalling, apoptosis/autophagy modelling and cytoskeletaldynamics mapping
  • Preclinical screening, SAR modelling and comparative mechanistic benchmarking

Side Effects and Risks

Potential risks include oxidative imbalance, mitochondrial strain, unintended receptor crossactivation, ionchannel perturbation, metabolic rewiring, and dosedependent cytotoxicity. High exposure may induce apoptosis, autophagy, inflammatory signalling or transcriptional destabilisation. Strict laboratory safety protocols and controlled handling conditions are required.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H23N3O4S

Molecular Weight

341.4 g/mol

CAS Number

23672-07-3

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

5.37e-01 g/L

Purity

Purity information is available upon request (COA).

Synonym

Levosulpiride; 23672-07-3; (-)-Sulpiride; Levopraid; Levopride

IUPAC/Chemical Name

N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide

InChl Key

BGRJTUBHPOOWDU-NSHDSACASA-N

InChl Code

InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/688272;

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download